Efficacy of chemotherapy according to BRCA status in patients with high-grade serous ovarian carcinoma at first platinum-sensitive relapse
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DOI: 10.1136/ijgc-2022-003993
Abstract: Objective Chemotherapy for high-grade serous ovarian cancers in platinum-sensitive relapse includes carboplatin/paclitaxel, carboplatin/gemcitabine, and carboplatin/pegylated liposomal doxorubicin. According to in vitro data, BRCA mutated patients are sensitive to replicative stress agents but BRCA status is… read more here.
Keywords: carboplatin; platinum sensitive; relapse; brca status ... See more keywords
Impact of BRCA Status on Reproductive Decision-Making and Self-Concept: A Mixed-Methods Study Informing the Development of Tailored Interventions
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DOI: 10.3390/cancers14061494
Abstract: Simple Summary Reproductive decision-making is a complex process and is influenced by personal, medical, and sociocultural factors. Relatively little is known about reproductive decision-making in women harboring mutations in the BRCA1 and/or BRCA2—pathogenic variants that… read more here.
Keywords: risk; brca status; decision; decision making ... See more keywords