Use of Germline BRCA Testing in Patients With Ovarian Cancer and Commercial Insurance
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.42703
Abstract: This cross-sectional study evaluates changes in the rate of germline BRCA testing among patients with ovarian cancer between 2008 and 2018 and analyzes factors associated with testing rates. read more here.
Keywords: patients ovarian; brca testing; germline brca; ovarian cancer ... See more keywords
BRCA testing and outcomes in women with breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-020-06038-x
Abstract: Main purpose Germline BRCA mutations ( BRCA m) strongly influence the risk of developing breast cancer. This study aimed to understand the role of BRCA m testing in affected individuals and to assess its impact… read more here.
Keywords: study; breast cancer; women breast; brca ... See more keywords
PCN254 - TRENDS IN BRCA TESTING OVER TIME AND SOCIOECONOMIC DEPRIVATION
Sign Up to like & getrecommendations! Published in 2018 at "Value in Health"
DOI: 10.1016/j.jval.2018.09.336
Abstract: OBJECTIVES: BRCA1&2 (BRCA) testing received much publicity following Angelina Jolie’s editorial ‘My Medical Choice’ in the New York Times on the 14th May 2013. In addition, in the UK, guidelines were updated by NICE (clinical… read more here.
Keywords: socioeconomic deprivation; deprivation; publication; brca testing ... See more keywords
BRCA testing on buccal swab to improve access to healthcare and cancer prevention: a performance evaluation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2022-003718
Abstract: Objective BRCA1/2 (BRCA) genetic testing allows patients with high-grade serous ovarian cancer to receive appropriate medical management with molecular target therapy and prevention strategies. Most of the BRCA sequencing methods use blood as the primary… read more here.
Keywords: brca testing; buccal swab; buccal swabs; cancer ... See more keywords
Abstract P2-12-06: Key factors influencing patient preferences for BRCA testing and adjuvant therapy in HER2-negative early breast cancer
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.sabcs24-p2-12-06
Abstract: Background: PARP inhibitors (PARPis) have survival benefits for women with high-risk HER2-negative early breast cancer (eBC) with germline BRCA mutations (BRCAm). Identifying patients eligible to receive PARPis can be challenging, as many individuals who are… read more here.
Keywords: adjuvant therapy; treatment; breast cancer; brca testing ... See more keywords
Assessment of BRCA testing uptake in ovarian cancer patients during the implementation of an oncologist-led genetic counseling model at an urban and suburban teaching hospital.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.1589
Abstract: 1589Background: BRCA testing has become an integral component of ovarian cancer management; however, low testing uptake remains an obstacle. This study evaluated the impact of an oncologist-led counseling and testing model on BRCA testing uptake.… read more here.
Keywords: testing uptake; cancer; oncology; oncologist led ... See more keywords
Real-world tumor BRCA testing patterns and PARP inhibitor use in HER2-negative metastatic breast cancer.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.1113
Abstract: 1113 Background: Testing for BRCA1/BRCA2 mutations (BRCAm) aids systemic treatment decisions for patients (pts) with metastatic breast cancer (mBC). This retrospective study explored real-world germline/tumor (g/t) BRCA testing patterns and PARP inhibitor (PARPi) use in… read more here.
Keywords: real world; brca testing; test; tumor ... See more keywords
Timely BRCA mutation testing in patients with metastatic prostate cancer: A comparative analysis between Medicare Advantage and traditional Medicare.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.5_suppl.319
Abstract: 319 Background: BRCA mutations have emerged as critical biomarkers for guiding the use of PARP inhibitors in metastatic prostate cancer. Timely access to BRCA testing remains a challenge, especially for those enrolled in Medicare Advantage… read more here.
Keywords: metastatic prostate; medicare; prostate cancer; brca testing ... See more keywords