Abstract P1-03-08: Clinico-pathological Characteristics of Breast Invasive Lobular Carcinoma in non-CDH1 genetic predisposition. Experience from the Institut Curie.
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DOI: 10.1158/1557-3265.sabcs24-p1-03-08
Abstract: Background: Invasive lobular carcinomas (ILC) represent 15% of breast cancers and are characterized by inactivation of E-cadherin (encoded by the CDH1 gene). Hereditary ILCs are rare and may be linked to germline mutations in CDH1,… read more here.
Keywords: cdh1; palb2; brca2 palb2; invasive lobular ... See more keywords
Germline pathogenic variants in BRCA1-, BRCA2- , and PALB2- genes among Ethiopian young women and men diagnosed with breast cancer.
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DOI: 10.1200/jco.2025.43.16_suppl.10567
Abstract: 10567 Background: Breast cancer incidence is rapidly increasing in low-and-middle-income countries (LMICs), where access to care is limited and survival outcome is poor. Young women and men are overrepresented among breast cancer (BC) patients diagnosed… read more here.
Keywords: breast cancer; brca1 brca2; young women; brca2 palb2 ... See more keywords
BRCA1, BRCA2 and PALB2 mRNA Expression as Prognostic Markers in Patients with Early Breast Cancer
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DOI: 10.3390/biomedicines12061361
Abstract: Breast cancer (BC) poses a challenge in establishing new treatment strategies and identifying new prognostic and predictive markers due to the extensive genetic heterogeneity of BC. Very few studies have investigated the impact of mRNA… read more here.
Keywords: breast cancer; brca2; brca2 palb2; mrna expression ... See more keywords