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Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-334
Abstract: Homologous recombination (HR) is an error-free repair pathway to eliminate DNA double-strand breaks and cells with deficiency of HR repair are highly sensitive to poly(ADP-ribose) polymerase (PARP) inhibitors. Thus, targeting HR-defective cells becomes a new…
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Keywords:
cancer;
functional biomarker;
detection brcaness;
brcaness functional ... See more keywords