Biocatalytic Aromaticity-Breaking Epoxidation of Naphthalene and Nucleophilic Ring-Opening Reactions
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DOI: 10.1021/acscatal.0c05588
Abstract: Aromatic hydroxylation reactions catalyzed by heme-thiolate enzymes proceed via an epoxide intermediate. These aromatic epoxides could be valuable building blocks for organic synthesis giving access to a range of chiral trans-disubstituted cyclohexadiene synthons. Here, we… read more here.
Keywords: ring opening; breaking epoxidation; nucleophilic ring; aromaticity breaking ... See more keywords