Identifying Balanced Chromosomal Translocations in Human Embryos by Oxford Nanopore Sequencing and Breakpoints Region Analysis
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DOI: 10.3389/fgene.2021.810900
Abstract: Background: Balanced chromosomal aberrations, especially balanced translocations, can cause infertility, recurrent miscarriage or having chromosomally defective offspring. Preimplantation genetic testing for structural rearrangement (PGT-SR) has been widely implemented to improve the clinical outcomes by selecting… read more here.
Keywords: oxford nanopore; analysis; breakpoints region; balanced chromosomal ... See more keywords