Genomic, immunological, and clinical analysis of COVID‐19 vaccine breakthrough infections in Beijing, China
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DOI: 10.1002/jmv.27636
Abstract: As the coronavirus disease 2019 (COVID‐19) pandemic is still ongoing and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants are circulating worldwide, an increasing number of breakthrough infections are being detected despite the good efficacy… read more here.
Keywords: vaccine breakthrough; group; covid vaccine; infections group ... See more keywords
Adverse events and breakthrough infections associated with COVID‐19 vaccination in the Indian population
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DOI: 10.1002/jmv.27708
Abstract: Vaccines against COVID‐19 provide immunity to deter severe morbidities associated with the infection. However, it does not prevent infection altogether in all exposed individuals. Furthermore, emerging variants of SARS‐CoV‐2 impose a threat concerning the competency… read more here.
Keywords: breakthrough infections; vaccination; indian population; adverse events ... See more keywords
Low‐frequency variants in mildly symptomatic vaccine breakthrough infections presents a doubled‐edged sword
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DOI: 10.1002/jmv.27726
Abstract: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants of concern (VOC) has raised questions regarding vaccine protection against SARS‐CoV‐2 infection, transmission, and ongoing virus evolution. Twenty‐three mildly symptomatic “vaccination breakthrough” infections were… read more here.
Keywords: breakthrough infections; frequency variants; low frequency; frequency ... See more keywords
SARS‐CoV‐2 vaccine antibody response and breakthrough infections in transplant recipients
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DOI: 10.1002/jmv.28736
Abstract: Rates and modulators of SARS‐CoV‐2 vaccine nonresponse and breakthrough infections remain unclear in serially vaccinated transplant recipients. In a prospective, mono‐centric, observational study, 1878 adult solid organ and hematopoietic cell transplant recipients, with prior SARS‐CoV‐2… read more here.
Keywords: breakthrough infections; antibody response; transplant recipients; vaccine ... See more keywords
Antigenic Imprinting and Immune Response Dynamics: Neutralization Against Emerging SARS‐CoV‐2 Omicron Variants Following Breakthrough Infections
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DOI: 10.1002/jmv.70681
Abstract: The recently mutated Omicron variant of SARS‐CoV‐2 exhibits extremely high infectivity and strong evolution and immune escape capabilities. Given the unique epidemic prevention policies of China, we collected 16 sets of sera from convalescent individuals… read more here.
Keywords: sars cov; antigenic imprinting; immune response; breakthrough infections ... See more keywords
SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses
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DOI: 10.1016/j.cell.2022.01.011
Abstract: Although infections among vaccinated individuals lead to milder COVID-19 symptoms relative to unvaccinated subjects, the specificity and durability of antibody responses elicited by breakthrough cases remain unknown. Here, we demonstrate that breakthrough infections induce serum… read more here.
Keywords: sars cov; cov breakthrough; neutralizing antibody; antibody ... See more keywords
Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants
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DOI: 10.1016/j.cell.2022.03.019
Abstract: Virus-like particle (VLP) and live virus assays were used to investigate neutralizing immunity against Delta and Omicron SARS-CoV-2 variants in 259 samples from 128 vaccinated individuals. Following Delta breakthrough infection, titers against WT rose 57-fold… read more here.
Keywords: omicron breakthrough; sars cov; delta; breakthrough infections ... See more keywords
The impact of COVID-19 vaccines on the Case Fatality Rate: The importance of monitoring breakthrough infections
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DOI: 10.1016/j.ijid.2022.03.059
Abstract: Objectives Test the behavior of the case fatality rate in a mixed population of vaccinated and unvaccinated individuals by illustrating the role of both the effectiveness of vaccines in preventing deaths and the detection of… read more here.
Keywords: breakthrough infections; fatality rate; case fatality;
Vaccine responses and hybrid immunity in people living with HIV after SARS-CoV-2 breakthrough infections
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DOI: 10.1038/s41541-024-00972-3
Abstract: The COVID-19 pandemic posed a challenge for people living with HIV (PLWH), particularly immune non-responders (INR) with compromised CD4 T-cell reconstitution following antiretroviral therapy (CD4 count read more here.
Keywords: sars cov; living hiv; people living; cov breakthrough ... See more keywords
Risk Factors Associated With Hospitalization and Death in COVID-19 Breakthrough Infections
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DOI: 10.1093/ofid/ofac116
Abstract: Abstract Background Characterizations of coronavirus disease 2019 (COVID-19) vaccine breakthrough infections are limited. We aim to characterize breakthrough infections and identify risk factors associated with outcomes. Methods This was a retrospective case series of consecutive… read more here.
Keywords: breakthrough infections; disease; factors associated; covid ... See more keywords
Longitudinal Analysis of SARS-CoV-2 Vaccine Breakthrough Infections Reveals Limited Infectious Virus Shedding and Restricted Tissue Distribution
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DOI: 10.1093/ofid/ofac192
Abstract: Abstract Background The global effort to vaccinate people against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during an ongoing pandemic has raised questions about how vaccine breakthrough infections compare with infections in immunologically naive individuals… read more here.
Keywords: breakthrough infections; virus shedding; infectious virus; sars cov ... See more keywords