Breakthrough Moments: Yoshiki Sasai's Discoveries in the Third Dimension.
Sign Up to like & getrecommendations! Published in 2019 at "Cell stem cell"
DOI: 10.1016/j.stem.2019.05.007
Abstract: Yoshiki Sasai pioneered the organoid field with his idea of mimicking embryonic development in 3D. We shine a spotlight on his seminal work describing how the innate ability of embryonic stem cells to self-organize into… read more here.
Keywords: discoveries third; third dimension; breakthrough moments; sasai discoveries ... See more keywords
Breakthrough Moments: Genome Editing and Organoids.
Sign Up to like & getrecommendations! Published in 2019 at "Cell stem cell"
DOI: 10.1016/j.stem.2019.05.008
Abstract: Six years ago, Schwank et al. (2013) adapted CRISPR-Cas9 and organoid technology to repair genetic diseases in patient-derived tissues. We shine a spotlight on how this work has inspired the development of tools to study and… read more here.
Keywords: breakthrough moments; editing organoids; moments genome; genome editing ... See more keywords