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Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines

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Published in 2018 at "Drug Design, Development and Therapy"

DOI: 10.2147/dddt.s152718

Abstract: Background A and B rings of the steroidal microtubule disruptor, 2-methoxyestradiol, and its analogs can be mimicked with a tetrahydroisoquinoline (THIQ) core. THIQs are cytotoxic agents with potential anticancer activities. The aim of this in… read more here.

Keywords: mda 231; cell death; based analogs; modes cell ... See more keywords