Triple-negative breast carcinomas of low malignant potential: review on diagnostic criteria and differential diagnoses
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03174-7
Abstract: Triple-negative breast carcinomas constitute a wide spectrum of lesions, mostly being highly aggressive. Nevertheless, some special histologic subtypes can have low malignant potential. The purpose of the present paper is to review diagnostic criteria and… read more here.
Keywords: breast carcinomas; negative breast; carcinoma; low malignant ... See more keywords
The immunotherapy candidate TNFSF4 may help the induction of a promising immunological response in breast carcinomas
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-98131-4
Abstract: Immune checkpoint blockade, an immunotherapy, has been applied in multiple systemic malignancies and has improved overall survival to a relatively great extent; whether it can be applied in breast cancer remains unknown. We endeavored to… read more here.
Keywords: breast carcinomas; immunotherapy; breast; breast cancer ... See more keywords
Abstract 3994: Differential regulation of hormone receptors and Ki67 in luminal breast carcinomas and tumor-adjacent mammary glands by mifepristone treatment
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3994
Abstract: Since antiprogestins inhibit the growth of preclinical mammary tumor models expressing higher levels of progesterone receptor (PR) isoform A (PRA) than isoform B (PRB), we designed a window-of-opportunity trial (MIPRA; NCT02651844) to study the benefits… read more here.
Keywords: luminal breast; expression; breast carcinomas; mammary glands ... See more keywords
The Assessment of HER2 Gene Status by Fluorescence In Situ Hybridization in Invasive Breast Carcinomas With Equivocal HER2 Immunostaining: Experience From a Single Institution
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Surgical Pathology"
DOI: 10.1177/1066896918767546
Abstract: Background. A subset of breast carcinomas harbors overexpression of the human epidermal growth factor receptor 2 (HER2). Fluorescence in situ hybridization (FISH) should be performed in breast carcinomas with equivocal HER2 immunostaining (immunohistochemistry [IHC] HER2… read more here.
Keywords: breast carcinomas; breast; her2 immunostaining; her2 ... See more keywords
Multifocal/Multicentric Ipsilateral Invasive Breast Carcinomas with Similar Histology: Is Multigene Testing of All Individual Foci Necessary?
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-018-6866-y
Abstract: BackgroundMultiple synchronous ipsilateral invasive breast carcinomas (BCs) with similar histology usually have concordant receptor status. It is unknown whether individual foci with similar histology also share molecular and biological similarities or are heterogenous. This study… read more here.
Keywords: breast carcinomas; similar histology; invasive breast; bcs ... See more keywords
Combined expression levels of KDM2A and KDM2B correlate with nucleolar size and prognosis in primary breast carcinomas.
Sign Up to like & getrecommendations! Published in 2020 at "Histology and histopathology"
DOI: 10.14670/hh-18-248
Abstract: Ribosome biogenesis is a fine-tuned cellular process and its deregulation is linked to cancer progression: tumors characterized by an intense ribosome biogenesis often display a more aggressive behavior. Ribosomal RNA (rRNA) synthesis is controlled at… read more here.
Keywords: kdm2a kdm2b; breast carcinomas; ribosome biogenesis; primary breast ... See more keywords
Role of germline variants in the metastasis of breast carcinomas
Sign Up to like & getrecommendations! Published in 2022 at "Oncotarget"
DOI: 10.18632/oncotarget.28250
Abstract: Most cancer-related deaths in breast cancer patients are associated with metastasis, a multistep, intricate process that requires the cooperation of tumour cells, tumour microenvironment and metastasis target tissues. It is accepted that metastasis does not… read more here.
Keywords: metastasis; germline variants; metastasis breast; role germline ... See more keywords
Primary neuroendocrine breast carcinomas: a retrospective analysis and review of literature
Sign Up to like & getrecommendations! Published in 2017 at "OncoTargets and therapy"
DOI: 10.2147/ott.s113736
Abstract: Background Primary neuroendocrine breast carcinomas (NEBCs) are a rare type of breast carcinomas that lack comprehensive recognition, including the clinicopathological features, therapeutic strategies, and prognostic significance. The aim of this retrospective analysis is to present… read more here.
Keywords: breast carcinomas; breast; analysis; histopathology ... See more keywords
Primary neuroendocrine breast carcinomas: a retrospective analysis and review of literature [Corrigendum]
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DOI: 10.2147/ott.s135552
Abstract: [This corrects the article on p. 397 in vol. 10, PMID: 28176908.]. read more here.
Keywords: breast carcinomas; analysis review; carcinomas retrospective; primary neuroendocrine ... See more keywords
Detection of Cellular Senescence Reveals the Existence of Senescent Tumor Cells within Invasive Breast Carcinomas and Related Metastases
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15061860
Abstract: Simple Summary Oncogene-induced senescence constitutes a barrier to carcinogenesis by arresting cells at risk of malignant transformation. However, numerous findings suggest that senescent cells conversely promote tumor growth and metastatic progression, for example, through the… read more here.
Keywords: tumor cells; breast carcinomas; senescence; tumor ... See more keywords
Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.68447
Abstract: Breast cancer heterogeneity in histology and molecular subtype influences metabolic and proliferative activity and hence the acid load on cancer cells. We hypothesized that acid-base transporters and intracellular pH (pHi) dynamics contribute inter-individual variability in… read more here.
Keywords: breast; proliferative activity; breast carcinomas; breast cancer ... See more keywords