Articles with "breast tumor" as a keyword



A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

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Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202515220

Abstract: A 3D cellular breast‐to‐brain tumor model is developed using thiolated‐hyaluronic‐acid‐based hydrogel cross‐linked with extracellular matrix (ECM) proteins collagen type IV, laminin‐211, and fibronectin to mimic the native‐brain ECM. The 3D model resembles the basement membrane… read more here.

Keywords: brain; presence; tumor; model ... See more keywords
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Suggested application of HER2+ breast tumor phenotype for germline TP53 variant classification within ACMG/AMP guidelines

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Published in 2020 at "Human Mutation"

DOI: 10.1002/humu.24060

Abstract: Early onset breast cancer is the most common malignancy in women with Li‐Fraumeni syndrome, caused by germline TP53 pathogenic variants. It has repeatedly been suggested that breast tumors from TP53 carriers are more likely to… read more here.

Keywords: her2 breast; breast; breast tumor; pathology ... See more keywords

Development of a Visible–Near Infrared Projected Multispectral Imaging System for Intraoperative Breast Tumor Margin Assessment

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Published in 2024 at "Journal of Biophotonics"

DOI: 10.1002/jbio.202400370

Abstract: A visible–near infrared (VIS–NIR) projected multispectral imaging (Proj‐MSI) system consisting of an MSI subsystem and a compact projector for intraoperative breast tumor margin assessment was developed. MSI with an average spectral resolution of 24 nm was… read more here.

Keywords: margin assessment; tumor; breast tumor; tumor margin ... See more keywords

High scattering sensitivity entropy imaging for breast tumor characterization and classification

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Published in 2025 at "Medical Physics"

DOI: 10.1002/mp.18063

Abstract: Diagnosing and characterizing breast lesions and tumors remains a common challenge in clinical practice. Ultrasound imaging stands out for its safety, real‐time capability, and affordability. However, the image quality of conventional ultrasound examination is limited,… read more here.

Keywords: sensitivity entropy; entropy imaging; high scattering; tumor ... See more keywords

Multiview Contouring for Breast Tumor on Magnetic Resonance Imaging

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Published in 2019 at "Journal of Digital Imaging"

DOI: 10.1007/s10278-019-00190-7

Abstract: The shape and contour of the lesion are shown to be effective features for physicians to identify breast tumor as benign or malignant. The region of the lesion is usually manually created by the physician… read more here.

Keywords: resonance imaging; breast tumors; breast tumor; magnetic resonance ... See more keywords

Phylloides: Uncommon ulcerated breast tumor diagnosed at Singida regional referral hospital. Case report

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Published in 2022 at "Annals of Medicine and Surgery"

DOI: 10.1016/j.amsu.2022.103301

Abstract: Phylloides tumor is rarely diagnosed in surgical clinics. There is high chance of missing of this kind of tumor by junior surgeons as it is also rarely explained in literature and diagnosed in our locality… read more here.

Keywords: tumor; uncommon ulcerated; phylloides uncommon; breast tumor ... See more keywords
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Application of immunotherapy based on dendritic cells stimulated by tumor cell-derived exosomes in a syngeneic breast tumor mouse model

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Published in 2021 at "Biochemistry and Biophysics Reports"

DOI: 10.1016/j.bbrep.2021.101136

Abstract: We here evaluated the therapeutic effect of tumor cell-derived exosomes (TEXs)-stimulated dendritic cells (DCs) in a syngeneic orthotopic breast tumor model. The DC line DC2.4 and breast cancer cell line E0771 originally isolated from C57BL/6… read more here.

Keywords: breast tumor; group; model; cell ... See more keywords

Disrupting PHF8-TOPBP1 connection elicits a breast tumor-specific vulnerability to chemotherapeutics.

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Published in 2022 at "Cancer letters"

DOI: 10.1016/j.canlet.2022.01.010

Abstract: The DNA damage response (DDR) pathway generally protects against genome instability, and defects in DDR have been exploited therapeutically in cancer treatment. We have reported that histone demethylase PHF8 demethylates TOPBP1 K118 mono-methylation (K118me1) to… read more here.

Keywords: breast tumor; phf8 topbp1; phf8; tumor specific ... See more keywords

Multispectral Optoacoustic Tomography in Assessment of Breast Tumor Margins During Breast‐Conserving Surgery: A First‐in‐human Case Study

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Published in 2018 at "Clinical Breast Cancer"

DOI: 10.1016/j.clbc.2018.07.026

Abstract: Multispectral Optoacoustic Tomography in Assessment of Breast Tumor Margins During Breast-Conserving Surgery: A First-in-human Case Study Yonggeng Goh, Ghayathri Balasundaram, Mohesh Moothanchery, Amalina Attia, Xiuting Li, Hann Qian Lim, Neal Burton, Yi Qiu, Thomas Choudary… read more here.

Keywords: tomography assessment; breast; breast tumor; assessment breast ... See more keywords

In vivo characteristics of human and mouse breast tumor cell lines.

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Published in 2019 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2019.04.009

Abstract: Although two- and three-dimensional in vitro studies of breast tumor cell lines have increased our knowledge on tumor growth and metastasis formation, the complex in vivo microenvironment is not taken into consideration. The goal of… read more here.

Keywords: breast tumor; cell lines; tumor cell; cell ... See more keywords

Investigating Lymphangiogenesis in a Sacrificially Bioprinted Volumetric Model of Breast Tumor Tissue.

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Published in 2020 at "Methods"

DOI: 10.1016/j.ymeth.2020.04.003

Abstract: Lymphatic vessels, as a means to metastasize, are frequently recruited by tumor tissues during their progression. However, reliable in vitro models to dissect the intricate crosstalk between lymphatic vessels and tumors are still in urgent… read more here.

Keywords: lymphangiogenesis; breast tumor; tissue; model ... See more keywords