Acteoside promotes B cell‐derived IL‐10 production and ameliorates autoimmunity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ma0422-510r
Abstract: IL‐10‐producing regulatory B (Breg) cells are well recognized for maintaining immune tolerance. The impaired Breg cell function with decreased IL‐10‐producing capacity has been found in autoimmune diseases, such as rheumatoid arthritis, lupus, and primary Sjogren's… read more here.
Keywords: ess mice; cell; cells ess; pathology ... See more keywords
Regulatory B Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-3532-1_8
Abstract: B cells are typically characterized by their ability to produce antibodies, function as secondary antigen-present cells, and produce various immunoregulatory cytokines. The regulatory B (Breg)-cell population is now widely accepted as an important modulatory component… read more here.
Keywords: regulatory cells; breg; breg cell; biology ... See more keywords
c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses
Sign Up to like & getrecommendations! Published in 2022 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-022-00948-6
Abstract: B cells secreting IL-10 functionally are recognized as functional regulatory B (Breg) cells; however, direct evidence concerning the phenotype, regulation, and functional and clinical relevance of IL-10-secreting Breg cells in humans is still lacking. Here,… read more here.
Keywords: inflammatory; functional breg; breg; functional regulatory ... See more keywords
B-117 Inverse Association Between Regulatory T and B Cells with HLA antibodies and Donor-specific Antibodies in Kidney Transplantation
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Chemistry"
DOI: 10.1093/clinchem/hvaf086.514
Abstract: Regulatory T cells (Tregs) and regulatory B cells (Bregs) were critical in maintaining immune tolerance. However, the relationships with Human Leukocyte antigen (HLA) antibody levels in kidney transplant recipients are not well understood. This study… read more here.
Keywords: breg; hla antibodies; dsa; regulatory cells ... See more keywords
IMBALANCE FAVOURING FOLLICULAR HELPER T CELLS OVER IL10+ REGULATORY B CELLS IS DETRIMENTAL FOR THE RENAL ALLOGRAFT
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation"
DOI: 10.1097/01.tp.0000698924.07922.54
Abstract: Background: A high frequency of regulatory B (Breg) cells, generally transitional B cells (Btrans), has been associated with long-term kidney allograft survival and operational tolerance, while circulating follicular helper T cells (cTfh) correlate with graft… read more here.
Keywords: breg cells; graft; breg; follicular helper ... See more keywords
Expanding Human Breg for Cellular Therapy in Transplantation: Time for Translation
Sign Up to like & getrecommendations! Published in 2024 at "Transplantation"
DOI: 10.1097/tp.0000000000005243
Abstract: Regulatory B cells (Breg) are instrumental in protecting allografts in transplantation. Breg signatures are identified in operationally tolerant human kidney transplant recipients and can predict organ survival and acute rejection. Animal models of transplantation and… read more here.
Keywords: breg; therapy; human breg; culture ... See more keywords
AB0161 CLINICAL ASSOCIATIONS AND DIAGNOSTIC POTENTIAL OF REGULATORY-LIKE B-CELLS IN SJOGREN’S SYNDROME
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.2614
Abstract: Background Some B-cell subsets contribute to the regulation of immune responses, mainly through the secretion of interleukin-10, which suppresses T-helper 1 (Th1) and Th17 cells and induces regulatory T-cells (Tregs). The role of Bregs and… read more here.
Keywords: absolute counts; none declared; cd24hicd27 cells; cd24hicd27 ... See more keywords
The Regulation between CD4+CXCR5+ Follicular Helper T (Tfh) Cells and CD19+CD24hiCD38hi Regulatory B (Breg) Cells in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/9003902
Abstract: Purpose T follicular helper (Tfh) cells and regulatory B (Breg) cells are reported to play essential roles in humoral immunity, especially in inflammation, autoimmune diseases, and cancer. Hence, we sought to investigate the involvement of… read more here.
Keywords: breg; tfh cells; gastric cancer; breg cells ... See more keywords
The Protective Effect of Esculentoside A on MPL/lpr Mice by Upregulating the Expression of CD19+IL-35+Breg Cells and Interleukin-35
Sign Up to like & getrecommendations! Published in 2024 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000541812
Abstract: Abstract Introduction: Esculentoside A (EsA) is one of the main components of the traditional Chinese medicine Phytolacca esculenta. The possible mechanism of action of EsA in the treatment of lupus nephritis (LN) was explored by… read more here.
Keywords: breg; breg cells; lpr mice; expression ... See more keywords
Düzenleyici B Hücreleri ve Kanserdeki Rolü
Sign Up to like & getrecommendations! Published in 2020 at "Southern Medical Journal"
DOI: 10.31832/smj.711179
Abstract: Humoral immun yanit elemani olan B hucreleri antikor uretiminden sorumlu hucrelerdir. Progenitor B hucreleri, kemik iliginde olgunlasirlar. B hucrelerinin yuzeyinde antijen reseptorleri, immunglobulin reseptorleri, adhezyon molekulleri ve Major Doku Uygunluk Kompleksin (MHC) molekulleri bulunur. Bu… read more here.
Keywords: kanserdeki rol; zenleyici creleri; breg; creleri kanserdeki ... See more keywords
Regulatory B Cells and Its Role in Central Nervous System Inflammatory Demyelinating Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01884
Abstract: Regulatory B (Breg) cells represent a population of suppressor B cells that participate in immunomodulatory processes and inhibition of excessive inflammation. The regulatory function of Breg cells have been demonstrated in mice and human with… read more here.
Keywords: breg cells; nervous system; central nervous; regulatory cells ... See more keywords