Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
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DOI: 10.1093/hmg/ddac127
Abstract: Mutations in genes encoding subunits of the BAF (BRG1/BRM-associated factor) complex cause various neurodevelopmental diseases. However, the underlying pathophysiology remains largely unknown. Here, we analyzed the function of Brg1, a core ATPase of BAF complexes,… read more here.
Keywords: brg1 causes; malformations cortical; cortical development; baf ... See more keywords