Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM
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DOI: 10.1161/circresaha.122.321956
Abstract: Background: The pathogenesis of MYBPC3-associated hypertrophic cardiomyopathy (HCM) is still unresolved. In our HCM patient cohort, a large and well-characterized population carrying the MYBPC3:c772G>A variant (p.Glu258Lys, E258K) provides the unique opportunity to study the basic… read more here.
Keywords: hcm; mybpc3; cross bridge; bridge cycling ... See more keywords