Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension
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DOI: 10.1093/nar/gkab173
Abstract: Abstract Nonenzymatic copying of RNA templates with activated nucleotides is a useful model for studying the emergence of heredity at the origin of life. Previous experiments with defined-sequence templates have pointed to the poor fidelity… read more here.
Keywords: bridged dinucleotides; activated mononucleotides; primer; rna ... See more keywords