Regioselective activation of benzocyclobutenones and dienamides lead to anti-Bredt bridged-ring systems by a [4+4] cycloaddition
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DOI: 10.1038/s41467-021-23344-0
Abstract: To the best of our knowledge, bridgehead carbon benzofused-bridged ring systems have previously not been accessible to the synthetic community. Here, we describe a formal type-II [4 + 4] cycloaddition approach that provides fully sp2-carbon embedded anti-Bredt… read more here.
Keywords: anti bredt; cycloaddition; ring systems; activation benzocyclobutenones ... See more keywords
An azo-bridged ring system enabled by-standing immobilization of a chiral diene ligand
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DOI: 10.1039/d1qo00852h
Abstract: A family of 9-azabicyclo[3.3.1]nonadiene ligands were developed, and the nitrogen atom in the bridged ring enables a facile immobilization of diene ligands to silica. read more here.
Keywords: immobilization; system enabled; diene; bridged ring ... See more keywords
Antibacterial and Cytotoxic Bridged and Ring Cleavage Angucyclinones From a Marine Streptomyces sp
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DOI: 10.3389/fchem.2020.00586
Abstract: Chemical investigation of a marine-derived Streptomyces sp. KCB-132, cultivated in liquid ISP2 medium, had led to the discovery of three C-ring cleavage angucyclinone N-heterocycles, pratensilins A–C, with a novel spiro indolinone-naphthofuran skeleton. Addition of 50… read more here.
Keywords: cleavage; ring cleavage; antibacterial cytotoxic; bridged ring ... See more keywords