Dual reactivity disulfide bridging reagents; enabling new approaches to antibody fragment bioconjugation
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DOI: 10.1039/d2sc04531a
Abstract: Disulfide bridging, also known as disulfide stapling, is a powerful strategy for the construction of site-selective protein bioconjugates. Here we describe the first examples of a new class of such reagents, containing a ‘stable-labile’ design.… read more here.
Keywords: reactivity disulfide; bioconjugation; bridging reagents; disulfide bridging ... See more keywords