Brillouin microscopy: an emerging tool for mechanobiology
Sign Up to like & getrecommendations! Published in 2019 at "Nature Methods"
DOI: 10.1038/s41592-019-0543-3
Abstract: The role and importance of mechanical properties of cells and tissues in cellular function, development and disease has widely been acknowledged, however standard techniques currently used to assess them exhibit intrinsic limitations. Recently, Brillouin microscopy,… read more here.
Keywords: brillouin microscopy; microscopy; emerging tool; tool mechanobiology ... See more keywords
Brillouin microscopy: assessing ocular tissue biomechanics
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Ophthalmology"
DOI: 10.1097/icu.0000000000000489
Abstract: Purpose of review Assessment of corneal biomechanics has been an unmet clinical need in ophthalmology for many years. Many researchers and clinicians have identified corneal biomechanics as source of variability in refractive procedures and one… read more here.
Keywords: corneal biomechanics; brillouin microscopy; microscopy; biomechanics ... See more keywords
In vivo assessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.220078
Abstract: In processes such as development and regeneration, where large cellular and tissue rearrangements occur, cell fate and behavior are strongly influenced by tissue mechanics. While most well-established tools probing mechanical properties require an invasive sample… read more here.
Keywords: regeneration; brillouin microscopy; microscopy; mechanical properties ... See more keywords
Contact-free single cell assay for assessing RBC mechanical properties using brillouin microscopy: Evaluation of anti-sickling therapeutics
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-6490
Abstract: Background: Brillouin microscopy is a non-contact, all-optical, label free technique, recently developed for biomechanical studies (elastic modulus and viscoelasticity). It is based on spontaneous Brillouin light scattering, an interaction between incident light and thermally generated… read more here.
Keywords: rbc; deformability; brillouin microscopy; hmf ... See more keywords
Quantifying cellular forces and biomechanical properties by correlative micropillar traction force and Brillouin microscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical optics express"
DOI: 10.1364/boe.10.002202
Abstract: Cells sense and respond to external physical forces and substrate rigidity by regulating their cell shape, internal cytoskeletal tension, and stiffness. Here we show that the combination of micropillar traction force and noncontact Brillouin microscopy… read more here.
Keywords: micropillar traction; brillouin microscopy; microscopy; force ... See more keywords
Multimodal quantitative optical elastography of the crystalline lens with optical coherence elastography and Brillouin microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Biomedical optics express"
DOI: 10.1364/boe.387361
Abstract: Assessing the biomechanical properties of the crystalline lens can provide crucial information for diagnosing disease and guiding precision therapeutic interventions. Existing noninvasive methods have been limited to global measurements. Here, we demonstrate the quantitative assessment… read more here.
Keywords: brillouin microscopy; microscopy; elastography; young modulus ... See more keywords
In vivo measurement of the biomechanical properties of human skin with motion-corrected Brillouin microscopy
Sign Up to like & getrecommendations! Published in 2024 at "Biomedical Optics Express"
DOI: 10.1364/boe.516032
Abstract: Biomechanical testing of human skin in vivo is important to study the aging process and pathological conditions such as skin cancer. Brillouin microscopy allows the all-optical, non-contact visualization of the mechanical properties of cells and… read more here.
Keywords: human skin; brillouin microscopy; motion corrected;
Impulsive stimulated Brillouin microscopy for non-contact, fast mechanical investigations of hydrogels.
Sign Up to like & getrecommendations! Published in 2019 at "Optics express"
DOI: 10.1364/oe.27.026910
Abstract: The mechanical properties of tissues and cells are increasingly recognized as an important feature for the understanding of pathological processes and as a diagnostic tool in biomedicine. Impulsive stimulated Brillouin scattering (ISBS) is promising to… read more here.
Keywords: stimulated brillouin; brillouin microscopy; microscopy; impulsive stimulated ... See more keywords
Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Optics letters"
DOI: 10.1364/ol.453996
Abstract: To understand the dynamics of tissue stiffness during neural tube formation and closure in a murine model, we have developed a multimodal, coaligned imaging system combining optical coherence tomography (OCT) and Brillouin microscopy. Brillouin microscopy… read more here.
Keywords: neural tube; system; brillouin microscopy; microscopy ... See more keywords
Depth-Dependent Reduction of Biomechanical Efficacy of Contact Lens-Assisted Corneal Cross-linking Analyzed by Brillouin Microscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of refractive surgery"
DOI: 10.3928/1081597x-20191004-01
Abstract: PURPOSE To determine the relative impact of contact lens- assisted corneal cross-linking (CACXL) and standard protocol CXL (CXL) on regional corneal stiffness using Brillouin microscopy. METHODS CXL and CACXL were performed on 30 intact fresh… read more here.
Keywords: cxl; brillouin microscopy; microscopy; stiffness ... See more keywords
Evaluation of Corneal Biomechanics Using Brillouin Microscopy in Chinese Adults With Myopia.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of refractive surgery"
DOI: 10.3928/1081597x-20240826-06
Abstract: PURPOSE To evaluate the corneal biomechanical metrics of Chinese adults with myopia and identify relevant factors of Brillouin microscopy. METHODS In this cross-sectional study, corneal biomechanics in Chinese adults with myopia were quantified and analyzed… read more here.
Keywords: brillouin microscopy; chinese adults; corneal; biomechanics ... See more keywords