Association of Central Nervous System Depression With Topical Brimonidine When Used for Hemostasis: A Serious Adverse Event
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2017.0247
Abstract: Importance Minor bleeding is the most common complication of dermatologic surgery. Topical brimonidine, 0.33%, gel has been reported for the use of hemostasis in dermatologic surgery. The safety profile and risk of systemic toxic effects… read more here.
Keywords: dermatology; brimonidine used; topical brimonidine; hemostasis ... See more keywords
Treatment of erythemato-telangiectatic rosacea with brimonidine alone or combined with vascular laser based on preliminary instrumental evaluation of the vascular component
Sign Up to like & getrecommendations! Published in 2017 at "Lasers in Medical Science"
DOI: 10.1007/s10103-017-2318-3
Abstract: The purpose of this study is to evaluate the outcome of a series of patients with erythematotelangiectatic rosacea (ETR) affected by persistent erythema and varying degree of telangiectasias being treated with brimonidine alone or combined… read more here.
Keywords: laser; treatment; brimonidine alone; evaluation ... See more keywords
Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits
Sign Up to like & getrecommendations! Published in 2019 at "Ophthalmology and Therapy"
DOI: 10.1007/s40123-019-0180-z
Abstract: IntroductionBrimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior ocular tissues… read more here.
Keywords: ocular tissues; posterior ocular; effect solution; solution ... See more keywords
Effect of brimonidine, an &agr;2 adrenergic agonist, on human meibomian gland epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2018.02.009
Abstract: ABSTRACT We recently discovered that the anti‐glaucoma pharmaceuticals timolol, a &bgr; adrenergic antagonist, and pilocarpine, a cholinergic compound, negatively influence the morphology, proliferative capacity and survival of human meibomian gland epithelial cells (HMGECs). We hypothesize… read more here.
Keywords: meibomian gland; epithelial cells; agr adrenergic; human meibomian ... See more keywords
A Case of Sterile Corneal Stromal Infiltration with Hypotonic Maculopathy Under Brimonidine Treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2022.2087687
Abstract: INTRODUCTION Brimonidine is a commonly used drug for glaucoma treatment, which has been linked to ocular autoimmune disorders like uveitis and conjunctivitis. Corneal pathology under brimonidine is generally less common. CASE DESCRIPTION Here, we report… read more here.
Keywords: brimonidine; hypotonic maculopathy; corneal; case ... See more keywords
Brimonidine and brinzolamide for treating glaucoma and ocular hypertension; a safety evaluation
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2017.1346083
Abstract: ABSTRACT Introduction: Brimonidine tartrate and brinzolamide eye drops are often used as third and fourth line treatment options to reduce intraocular pressure (IOP) in the management of glaucoma and ocular hypertension. Better tolerated, more effective… read more here.
Keywords: brimonidine; ocular hypertension; safety; glaucoma ocular ... See more keywords
Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy‐related postinflammatory hyperpigmentation
Sign Up to like & getrecommendations! Published in 2018 at "Dermatologic Therapy"
DOI: 10.1111/dth.12657
Abstract: Brimonidine gel, originally approved for the treatment of facial rosacea, causes direct vasoconstriction and possesses extensive utilization in dermatologic fields. A Q‐switched (QS) neodymium‐doped yttrium aluminum garnet (Nd:YAG) laser is generally used to treat solar… read more here.
Keywords: laser; gel; therapy; postinflammatory hyperpigmentation ... See more keywords
Rapid and sustained improvement of dupilumab‐associated head and neck erythema with topical brimonidine
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15471
Abstract: Dear Editor, Recalcitrant head and neck erythema (RHNE) is an adverse effect that has been observed in patients treated with dupilumab with a frequency that varies from 3% to 10%. However, currently its management remains… read more here.
Keywords: improvement; head neck; brimonidine; plus hydrocortisone ... See more keywords
Efficacy and safety of topical brimonidine in dermatology: A review article
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15819
Abstract: Brimonidine is a vasoconstrictive agent used to treat several dermatologic disorders. Here, we review the uses of brimonidine in different aspects of dermatology. We searched keywords including rosacea, erythema, topical brimonidine, dermatology, and skin disease… read more here.
Keywords: brimonidine; dermatology; brimonidine dermatology; safety topical ... See more keywords
Reduction in ultraviolet B light–induced erythema by oxymetazoline and brimonidine is mediated by different α‐adrenoceptors
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13557
Abstract: When applied topically, oxymetazoline and brimonidine reduce the persistent facial erythema of rosacea; this effect is mediated by cutaneous vasoconstriction induced by postsynaptic activation of α‐adrenoceptors. We investigated the α‐adrenergic pharmacology of oxymetazoline and brimonidine.… read more here.
Keywords: induced erythema; oxymetazoline brimonidine; pharmacology; ultraviolet light ... See more keywords
In vitro and in vivo evaluation of brimonidine loaded silica nanoparticles-laden silicone contact lenses to manage glaucoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomaterials Applications"
DOI: 10.1177/08853282221090880
Abstract: Glaucoma is treated by frequent instillation of 0.2% w/v brimonidine tartrate eye drop solution, which showed poor ocular bioavailability of 1–3%. Medicated contact lenses can be used to improve the ocular drug bioavailability. However, drug… read more here.
Keywords: silica nanoparticles; brimonidine; bri lens; contact lens ... See more keywords