Single quad Mass analyzer coupled UPLC method for impurity profile of Brimonidine tartrate and Timolol maleate: Application in their binary mixture ophthalmic formulation.
Sign Up to like & getrecommendations! Published in 2021 at "Annales pharmaceutiques francaises"
DOI: 10.1016/j.pharma.2021.02.006
Abstract: The main objective of the study is to develop a suitable and rapid UPLC/PDA method by coupling online to Quadrupole Dalton analyzer (QDa), a mass detector for the identification and impurity profiling of Brimonidine Tartrate… read more here.
Keywords: method; timolol maleate; brimonidine tartrate; ophthalmic formulation ... See more keywords
Novel long-acting brimonidine tartrate loaded-PCL/PVP nanofibers for versatile biomedical applications: fabrication, characterization and antimicrobial evaluation
Sign Up to like & getrecommendations! Published in 2023 at "RSC Advances"
DOI: 10.1039/d3ra02244g
Abstract: The global state of antibiotic resistance highlights the necessity for new drugs that can treat a wide range of microbial infections. Drug repurposing has several advantages, including lower costs and improved safety compared to developing… read more here.
Keywords: brimonidine tartrate; pcl pvp; drug;
Inflammatory Cells and Lipid Deposits Detected by in Vivo Confocal Microscopy in Brimonidine Tartrate Ophthalmic Solution-Related Corneal Disorders: A Case Series.
Sign Up to like & getrecommendations! Published in 2022 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2022.2137045
Abstract: We reviewed the medical charts of five patients diagnosed with brimonidine tartrate (BT)-related corneal disorders. A fan-shaped corneal opacity was present in four patients and limbal corneal infiltrations were present in one patient. In vivo… read more here.
Keywords: fan shaped; microscopy; related corneal; opacity ... See more keywords
Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery"
DOI: 10.1080/10717544.2019.1609622
Abstract: Abstract Brimonidine tartrate (BRT) is a hydrophilic α2 adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment. Owing to the obstacles… read more here.
Keywords: improve ocular; delivery; vivo pharmacodynamic; brimonidine tartrate ... See more keywords
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2022.2112948
Abstract: ABSTRACT Introduction Ocular redness, or conjunctival hyperemia, is a common ophthalmic sign associated with reduced quality of life. For redness without apparent underlying pathology, topical ophthalmic decongestants have been widely used. Areas covered Brimonidine tartrate… read more here.
Keywords: safety; redness; relief; ocular redness ... See more keywords
Severe Corneal Disorders Developed After Brimonidine Tartrate Ophthalmic Solution Use
Sign Up to like & getrecommendations! Published in 2017 at "Cornea"
DOI: 10.1097/ico.0000000000001370
Abstract: Purpose: The primary side effects associated with 0.1% brimonidine tartrate (BT) ophthalmic solution with sodium chlorite are allergic conjunctivitis, blepharitis, and conjunctival hyperemia. However, cornea-related side effects are rare. In this study, we report 2… read more here.
Keywords: corneal; use; brimonidine tartrate; tartrate ophthalmic ... See more keywords
Treatment of Ptosis Using Brimonidine Tartrate for Anterior Laminectomy-Induced Horner Syndrome.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Ophthalmology"
DOI: 10.1097/wno.0000000000000826
Abstract: H orner syndrome is characterized by the presence of a lesion at any location along the oculosympathetic pathway. It is clinically characterized by ipsilateral pupillary miosis, facial anhidrosis, ipsilateral upper eyelid ptosis, and mild lower… read more here.
Keywords: ptosis; muscle; brimonidine tartrate; artery ... See more keywords
Effect of brimonidine tartrate on basophil activation in glaucoma patients.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2020.03.21
Abstract: AIM To evaluate the mechanism of which brimonidine tartrate 0.15% causes clinical hypersensitivity. METHODS A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to a control group consisting 13 healthy volunteers.… read more here.
Keywords: basophil activation; brimonidine tartrate; activation; brimonidine ... See more keywords
Augmented in vitro and in vivo Profiles of Brimonidine Tartrate Using Gelatinized-Core Liposomes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s370192
Abstract: Abstract Background The low entrapment efficiency of the hydrophilic drugs such as brimonidine tartrate (BRT) in liposomes represents a challenge that requires interventions. Gelatinized core liposomes (GCLs) were fabricated to increase the drug entrapment, corneal… read more here.
Keywords: brimonidine tartrate; gelatinized core; core liposomes; vitro vivo ... See more keywords
Effects of brimonidine tartrate 0.2 and 0.15% ophthalmic solution on the static and dynamic pupil characteristics
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1160414
Abstract: Aims To investigate the differences between 0.2 and 0.15% brimonidine tartrate eye drops for anti-mydriatic effects and the optical quality under different light conditions. Methods This prospective study involved 80 consecutive high myopia patients undergoing… read more here.
Keywords: tartrate eye; group; static dynamic; dynamic pupil ... See more keywords