CASP8, XRCC1, WRN, NF2, and BRIP1 Polymorphisms Analysis Shows Their Genetic Susceptibility for Meningioma Risk and the Association with Tumor-Related Phenotype in a Chinese Population.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.03.108
Abstract: OBJECTIVE To investigate 10 candidate single nucleotide polymorphisms (SNPs) in 5 genes (CASP8, XRCC1, WRN, NF2, and BRIP1) to confirm the association between the 5 genes and the meningioma risk in a Chinese population. METHODS… read more here.
Keywords: risk; brip1; association; meningioma risk ... See more keywords
Novel role of BRCA1 interacting C‐terminal helicase 1 (BRIP1) in breast tumour cell invasion
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15761
Abstract: Breast cancer (BC) is the most common malignancy and the leading cause of death in women worldwide. Only 5%‐10% of mutations in BRCA genes are associated with familial breast tumours in Eastern countries, suggesting the… read more here.
Keywords: cell proliferation; brip1; role; cell invasion ... See more keywords
Leptomeningeal disease in BRIP1-mutated pancreatic adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-249837
Abstract: Leptomeningeal disease is rare in pancreatic cancer and prognosis remains poor. Mutation profiles are now directing therapy to improve survival. We describe a case of leptomeningeal and brain metastasis in BRCA1 interacting protein 1, or… read more here.
Keywords: brip1; mutated pancreatic; pancreatic adenocarcinoma; brip1 mutated ... See more keywords
A single-institution and commercial laboratory database analysis of BRIP1-associated cancer risks.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.1538
Abstract: 1538Background: BRIP1/FANCJ participates in DNA replication and repair via interactions with BRCA1 and possibly MLH1. Previous studies have reported that pathogenic variants (PV) in BRIP1 are assoc... read more here.
Keywords: brip1; laboratory database; commercial laboratory; single institution ... See more keywords
BRIP1 coding variants are associated with a high risk of hepatocellular carcinoma occurrence in patients with HCV- or HBV-related liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.11327
Abstract: The molecular mechanisms of hepatocellular carcinoma (HCC) carcinogenesis are still not fully understood. DNA repair defects may influence HCC risk. The aim of the study was to look for potential genetic variants of DNA repair… read more here.
Keywords: liver disease; brip1; risk; hcc risk ... See more keywords