Two BRM promoter polymorphisms predict poor survival in patients with hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22736
Abstract: Polymorphisms in the promoter of the BRM gene, a critical subunit of the chromatin remodeling SWI/SNF complex, have previously been implicated in risk and prognosis in Caucasian‐predominant lung, head and neck, esophageal, and pancreatic cancers,… read more here.
Keywords: hepatocellular carcinoma; risk; two brm; promoter ... See more keywords
Association of two BRM promoter polymorphisms and smoking status with malignant pleural mesothelioma risk and prognosis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23088
Abstract: Brahma (BRM), of the SWI/SNF complex, has two 6 to 7 bp insertion promoter polymorphisms (BRM‐741/BRM‐1321) that cause epigenetic BRM suppression, and are associated with risk of multiple cancers. BRM polymorphisms were genotyped in malignant pleural… read more here.
Keywords: risk; prognosis; association; smoking status ... See more keywords
The Bayes Recognition Model for Mine Water Inrush Source Based on Multiple Logistic Regression Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Mine Water and the Environment"
DOI: 10.1007/s10230-020-00699-2
Abstract: Accurate recognition of water inrush sources is important in mine water hazard control. In this study, 118 water samples of four water types in the Qinan coal mine were analysed by multiple logistic regression, and… read more here.
Keywords: die; mlra brm; water; mlra ... See more keywords
Formulations of Pseudomonas fluorescens and Burkholderia pyrrocinia control rice blast of upland rice cultivated under no-tillage system
Sign Up to like & getrecommendations! Published in 2020 at "Biological Control"
DOI: 10.1016/j.biocontrol.2019.104153
Abstract: Abstract Leaf blast caused by Magnaporthe oryzae is among the major diseases that limit rice productivity in the world, and control of the disease occurs, basically, through the application of fungicides. Control methods such as… read more here.
Keywords: blast; rice; control; rice blast ... See more keywords
BRM transcriptionally regulates miR-302a-3p to target SOCS5/STAT3 signaling axis to potentiate pancreatic cancer metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.02.031
Abstract: Brahma (BRM) has recently been documented as a significant predictor of pancreatic cancer (PC) metastasis. This study aimed to further elucidate molecular mechanism by which BRM promotes PC metastasis. We found that silencing BRM reduced… read more here.
Keywords: brm; mir 302a; cancer metastasis; pancreatic cancer ... See more keywords
Impact of EGFR mutation on outcomes following SRS for brain metastases in non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Lung cancer"
DOI: 10.1016/j.lungcan.2021.02.036
Abstract: INTRODUCTION Patients with EGFR-mutated (EGFRm) non-small cell lung cancer (NSCLC) are at particularly high risk of developing brain metastases (BrM). In addition to EGFR targeting tyrosine kinase inhibitors (TKI), radiosurgery (SRS) has an important role… read more here.
Keywords: non small; brm; srs; lung cancer ... See more keywords
Downregulation of PARP1 transcription by promoter-associated E2F4-RBL2-HDAC1-BRM complex contributes to repression of pluripotency stem cell factors in human monocytes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10307-z
Abstract: Differentiation of certain cell types is followed by a downregulation of PARP1 expression. We show that the reduction in the abundance of PARP1 in hematopoietic progenitor cells and monocytes is tightly controlled by the cell… read more here.
Keywords: transcription; downregulation parp1; hdac1; parp1 ... See more keywords
Fatty acid synthase: a druggable driver of breast cancer brain metastasis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2077189
Abstract: ABSTRACT Introduction Brain metastasis (BrM) is a key contributor to morbidity and mortality in breast cancer patients, especially among high-risk epidermal growth factor receptor 2-positive (HER2+) and triple-negative/basal-like molecular subtypes. Optimal management of BrM is… read more here.
Keywords: metastasis; brm; breast cancer; brain ... See more keywords
Motivating Proactive Biorisk Management
Sign Up to like & getrecommendations! Published in 2023 at "Health Security"
DOI: 10.1089/hs.2022.0101
Abstract: Scholars and practitioners of biosafety and biosecurity (collectively, biorisk management or BRM) have argued that life scientists should play a more proactive role in monitoring their work for potential risks, mitigating harm, and seeking help… read more here.
Keywords: brm; life scientists; promote proactive; biorisk management ... See more keywords
Significance of R1-resection at the bronchial margin after surgery for non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Cardio-Thoracic Surgery"
DOI: 10.1093/ejcts/ezw242
Abstract: OBJECTIVES We aimed to evaluate the significance of microscopic residual disease at the bronchial resection margin (R1-BRM) after curative surgery for non-small cell lung cancer (NSCLC). METHODS Retrospective review was performed on 1800 patients from… read more here.
Keywords: surgery; disease; overall survival; resection ... See more keywords
STARGARDT DISEASE: Beyond Flecks and Atrophy
Sign Up to like & getrecommendations! Published in 2017 at "Retina"
DOI: 10.1097/iae.0000000000001484
Abstract: Purpose: To identify changes in the outer retina in areas without atrophy or flecks of Stargardt disease (STGD) using spectral-domain optical coherence tomography. Methods: Twenty-three STGD patients and 26 control subjects were assessed for outer… read more here.
Keywords: outer retina; disease; stgd patients; brm ... See more keywords