Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.
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DOI: 10.1016/j.celrep.2019.04.063
Abstract: Guanylate-binding protein (GBP) 5 is an interferon (IFN)-inducible cellular factor reducing HIV-1 infectivity by an incompletely understood mechanism. Here, we show that this activity is shared by GBP2, but not by other members of the… read more here.
Keywords: exert broad; broad antiviral; guanylate binding; envelope ... See more keywords