KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
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DOI: 10.1038/s41556-020-0494-z
Abstract: The importance of germline-inherited post-translational histone modifications on priming early mammalian development is just emerging 1 – 4 . Histone H3 lysine 9 (H3K9) trimethylation is associated with heterochromatin and gene repression during cell-fate change… read more here.
Keywords: broad h3k4me3; maternal zygotic; zygotic transition; kdm4a ... See more keywords