Supramolecular Photonic Elastomers with Brilliant Structural Colors and Broad‐Spectrum Responsiveness
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202000008
Abstract: Photonic elastomers (PEs) that can tune their colors through adjusting the lattice spacing of incorporated colloidal particles during mechanical deformation have shown great promise in visualized strain/stress sensors. However, the unsatisfactory structural color and narrow‐spectrum… read more here.
Keywords: photonic elastomers; fe3o4 nps; spectrum responsiveness; broad spectrum ... See more keywords
Lipid Nanoparticles for Broad‐Spectrum Nucleic Acid Delivery
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202101391
Abstract: Lipid nanoparticles (LNPs) are the most advanced nonviral modality for nucleic acid (NA) delivery, and have recently gained enormous attention in the fields of RNA therapeutics and vaccine development. Here, ionizable adamantane‐based lipidoids named XMaNs,… read more here.
Keywords: lipid nanoparticles; delivery; acid delivery; nanoparticles broad ... See more keywords
Broad‐Spectrum Antiviral Agents Based on Multivalent Inhibitors of Viral Infectivity
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202001433
Abstract: Abstract The ongoing pandemic of the coronavirus disease (Covid‐19), caused by the spread of the severe acute respiratory syndrome coronavirus 2 (SARS CoV‐2), highlights the need for broad‐spectrum antiviral drugs. In this Essay, it is… read more here.
Keywords: multivalent inhibitors; spectrum antiviral; inhibitors viral; broad spectrum ... See more keywords
A Broad‐Spectrum ROS‐Eliminating Material for Prevention of Inflammation and Drug‐Induced Organ Toxicity
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201800781
Abstract: Abstract Despite the great potential of numerous antioxidants for pharmacotherapy of diseases associated with inflammation and oxidative stress, many challenges remain for their clinical translation. Herein, a superoxidase dismutase/catalase‐mimetic material based on Tempol and phenylboronic… read more here.
Keywords: inflammation; drug induced; induced organ; broad spectrum ... See more keywords
Rational Development of Hypervalent Glycan Shield‐Binding Nanoparticles with Broad‐Spectrum Inhibition against Fatal Viruses Including SARS‐CoV‐2 Variants
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202689
Abstract: Infectious virus diseases, particularly coronavirus disease 2019, have posed a severe threat to public health, whereas the developed therapeutic and prophylactic strategies are seriously challenged by viral evolution and mutation. Therefore, broad‐spectrum inhibitors of viruses… read more here.
Keywords: hypervalent glycan; spectrum inhibition; binding nanoparticles; sars cov ... See more keywords
Pectinases as promising green biocatalysts having broad-spectrum applications: Recent trends, scope and relevance.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2464
Abstract: Pectinases are a collection of multiple enzymes which have a common substrate i.e., pectin. They can act on different parts of pectin due to the structural heterogeneity of pectin. Therefore, they have been placed in… read more here.
Keywords: green biocatalysts; biocatalysts broad; pectinases promising; spectrum applications ... See more keywords
STA‐55, an Easily Accessible, Broad‐Spectrum, Activity‐Based Aldehyde Dehydrogenase Probe
Sign Up to like & getrecommendations! Published in 2020 at "ChemBioChem"
DOI: 10.1002/cbic.201900771
Abstract: Aldehyde dehydrogenases (ALDHs) convert aldehydes into carboxylic acids and are often upregulated in cancer. They have been linked to therapy resistance and are therefore potential therapeutic targets. However, only a few selective and potent inhibitors… read more here.
Keywords: probe; activity based; spectrum activity; broad spectrum ... See more keywords
Broad‐Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View
Sign Up to like & getrecommendations! Published in 2020 at "ChemMedChem"
DOI: 10.1002/cmdc.202000464
Abstract: Infections by flaviviruses, such as Dengue, West Nile, Yellow Fever and Zika viruses, represent a growing risk for global health. There are vaccines only for few flaviviruses while no effective treatments are available. Flaviviruses share… read more here.
Keywords: flavivirus inhibitors; chemistry; inhibitors medicinal; broad spectrum ... See more keywords
Broad‐Spectrum Antifungal Agents: Fluorinated Aryl‐ and Heteroaryl‐Substituted Hydrazones
Sign Up to like & getrecommendations! Published in 2020 at "ChemMedChem"
DOI: 10.1002/cmdc.202000626
Abstract: Fluorinated aryl‐ and heteroaryl‐substituted monohydrazones displayed excellent broad‐spectrum activity against various fungal strains, including a panel of clinically relevant Candida auris strains relative to a control antifungal agent, voriconazole (VRC). These monohydrazones displayed less hemolysis… read more here.
Keywords: spectrum antifungal; fluorinated aryl; heteroaryl substituted; aryl heteroaryl ... See more keywords
Reversible Broad‐Spectrum Control of Selective Reflections of Chiral Nematic Phases by Closed‐/Open‐Type Axially Chiral Azo Dopants
Sign Up to like & getrecommendations! Published in 2017 at "ChemistryOpen"
DOI: 10.1002/open.201700170
Abstract: Abstract Invited for this month's cover picture is the groups of Professor Hirotsugu Kikuchi and Dr. Yasushi Okumura at the Institute for Materials Chemistry and Engineering at Kyushu University (Japan). External dynamic control of molecular… read more here.
Keywords: chiral nematic; closed open; control; reversible broad ... See more keywords
Florylpicoxamid, a New Picolinamide Fungicide with Broad Spectrum Activity.
Sign Up to like & getrecommendations! Published in 2021 at "Pest management science"
DOI: 10.1002/ps.6483
Abstract: BACKGROUND Following the introduction of fenpicoxamid, a natural product-based fungicide targeting the Qi site of mitochondrial cytochrome bc1 complex, a second generation fully synthetic picolinamide, florylpicoxamid, was discovered and its biological activity and attributes were… read more here.
Keywords: new picolinamide; activity florylpicoxamid; florylpicoxamid new; broad spectrum ... See more keywords