Brodalumab to the Rescue: Efficacy and Safety of Brodalumab in Patients with Psoriasis and Prior Exposure or Inadequate Response to Biologics
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DOI: 10.1007/s13555-020-00411-w
Abstract: While biologic therapies for psoriasis are effective for many patients, some patients may lose response, have inadequate control of disease, or develop intolerance to certain biologic agents. It may therefore be beneficial for patients whose psoriasis… read more here.
Keywords: response; efficacy safety; brodalumab patients; exposure ... See more keywords
Impact du brodalumab sur la qualité de vie des patients chez des patients psoriasiques atteints de rhumatisme psoriasique : analyse post-hoc des études AMAGINE 2/3
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DOI: 10.1016/j.annder.2020.09.532
Abstract: Introduction Dans les etudes AMAGINE 2/3, le brodalumab est associe a un blanchiment total et a une amelioration de la qualite de vie chez les patients atteints d’un psoriasis en plaques modere a severe. L’objectif… read more here.
Keywords: sur; vie; pso seul; brodalumab ... See more keywords
Efficacy and safety of brodalumab in patients with psoriasis who had inadequate responses to ustekinumab: subgroup analysis of two randomized phase III trials
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DOI: 10.1111/bjd.17318
Abstract: Brodalumab, a fully human anti‐interleukin‐17 receptor A monoclonal antibody, has demonstrated superior efficacy and safety over ustekinumab as induction therapy for moderate‐to‐severe psoriasis. read more here.
Keywords: safety brodalumab; efficacy safety; brodalumab patients; brodalumab ... See more keywords
Ixekizumab and brodalumab indirect comparison in the treatment of moderate to severe psoriasis: Results from an Italian single‐center retrospective study in a real‐life setting
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DOI: 10.1111/dth.15667
Abstract: Eleven biologic drugs are currently approved for psoriasis management. Real‐life studies are needed to guide clinicians in choosing a tailored‐tail therapy. The aim of our retrospective study is to indirectly compare the efficacy and safety… read more here.
Keywords: real life; ixekizumab brodalumab; brodalumab; psoriasis ... See more keywords
Efficacy of Brodalumab for Moderate to Severe Plaque Psoriasis: A Canadian Network Meta-Analysis
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DOI: 10.1177/1203475420933174
Abstract: Background Several treatments for plaque psoriasis are available, but it remains challenging for physicians to make informed treatment decisions due to a lack of head-to-head trials. Objectives This network meta-analysis (NMA) compares the efficacy of… read more here.
Keywords: severe plaque; efficacy; brodalumab; psoriasis ... See more keywords
Brodalumab for Plaque Psoriasis: A Canadian Real-World Experience at 2-Years Post-Launch.
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DOI: 10.1177/12034754231168851
Abstract: BACKGROUND There is limited real-life evidence with brodalumab in patients with plaque psoriasis in Canada. OBJECTIVES To examine real-world effectiveness of brodalumab in Canadian routine care with a focus on clinician and patient-reported outcomes, as… read more here.
Keywords: plaque psoriasis; brodalumab; real world; continuation rates ... See more keywords
Brodalumab in an Organ Transplant Recipient With Psoriasis.
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DOI: 10.12788/cutis.0167
Abstract: Immunocompromised patients, such as organ transplant recipients, require careful benefit-risk consideration when selecting a systemic agent for psoriasis. Brodalumab is an immunomodulatory biologic that binds to and inhibits IL-17RA, thereby inhibiting the actions of IL-17A,… read more here.
Keywords: organ transplant; transplant recipient; brodalumab organ; brodalumab ... See more keywords
Excessive hair growth in a patient with psoriatic erythroderma following secukinumab administration
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DOI: 10.1684/ejd.2018.3327
Abstract: 539 sified as a localized form of pustular psoriasis. In addition, a recent report has revealed that there is no clear genetic difference between PPP and PPPP [4]. On the other hand, previous studies have… read more here.
Keywords: psoriasis vulgaris; brodalumab; psoriasis; receptor ... See more keywords