Cytotoxic Effect of Bromelain on HepG2 Hepatocellular Carcinoma Cell Line
Sign Up to like & getrecommendations! Published in 2021 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-021-03505-z
Abstract: Cancer is a complicated long-term disease due to computable key molecular players involved in aggravating the disease. Among various kinds of cancer, hepatocellular carcinoma (HCC) is the ninth leading cause of cancer. Recently, plant-based products… read more here.
Keywords: hepatocellular carcinoma; bromelain hepg2; cell; bromelain ... See more keywords
Determination of the Crystal Structure and Substrate Specificity of Ananain.
Sign Up to like & getrecommendations! Published in 2019 at "Biochimie"
DOI: 10.1016/j.biochi.2019.07.011
Abstract: Ananain (EC 3.4.22.31) accounts for less than 10% of the total enzyme in the crude pineapple stem extract known as bromelain, yet yields the majority of the proteolytic activity of bromelain. Despite a high degree… read more here.
Keywords: bromelain; ananain; specificity ananain; crystal ... See more keywords
A high efficiency method combining metal chelate ionic liquid-based aqueous two-phase flotation with two-step precipitation process for bromelain purification.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.125749
Abstract: This work was to develop a cost-effective and sustainable method which included metal chelate ionic liquid-based aqueous two-phase flotation (IL-based ATPF) and a two-step precipitation process for purifying bromelain from pineapple. Firstly, the metal chelate… read more here.
Keywords: bromelain; two step; method; metal chelate ... See more keywords
The mechanistic effect of bromelain and papain on tenderization in jumbo squid (Dosidicus gigas) muscle.
Sign Up to like & getrecommendations! Published in 2020 at "Food research international"
DOI: 10.1016/j.foodres.2020.108991
Abstract: Jumbo squid (Dosidicus gigas) muscle is rather hard and tough, which directly affects consumer acceptance. In this study, the tenderization effect of bromelain and papain on squid muscle during enzymolysis is examined and compared with… read more here.
Keywords: bromelain; tenderization; muscle; water ... See more keywords
Immobilization of bromelain and ZnO nanoparticles on silk fibroin nanofibers as an antibacterial and anti-inflammatory burn dressing.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121227
Abstract: Burns is a critical fatal event due to the risk of infection and complex inflammatory cascades. This study aimed to fabricate and characterize a new antibacterial and anti-inflammatory dressing for second-degree burns by the immobilization… read more here.
Keywords: bromelain zno; bromelain; zno nps; zno ... See more keywords
Characterization of bromelain indicates a molar excess of inhibitor vs. enzyme molecules, a Jacalin-like lectin and Maillard reaction products.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.113075
Abstract: The phytotherapeutic bromelain is a heterogeneous protein mixture, extracted from pineapple stem, with high proteolytic activity based on cysteine proteases. Its global protein chemical composition was analyzed qualitatively and quantitatively by SDS-PAGE and RP-HPLC. A… read more here.
Keywords: maillard reaction; inhibitor; inhibitor enzyme; bromelain ... See more keywords
Implications of designing a bromelain loaded enteric nanoformulation on its stability and anti-inflammatory potential upon oral administration
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c7ra13555f
Abstract: The objective of the present investigation was to develop an enteric nano-formulation of bromelain to improve its stability and anti-inflammatory potential. Bromelain loaded nanoparticles (Br-NPs) were developed using a Eudragit L 100 polymer by a… read more here.
Keywords: anti inflammatory; bromelain; stability anti; bromelain loaded ... See more keywords
Enzymatic Hydrolysis of Catfish (Pangasius hypophthalmus) By-Product: Kinetic Analysis of Key Process Parameters and Characteristics of the Hydrolysates Obtained
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Aquatic Food Product Technology"
DOI: 10.1080/10498850.2017.1376027
Abstract: ABSTRACT In this study, kinetic evaluation of enzymatic hydrolysis of catfish (Pangasius hypophthalmus) by-product meat was conducted. The effects of key factors such as type of proteases (neutrase, papain, and bromelain), enzyme to substrate ratio… read more here.
Keywords: bromelain; product; process; hydrolysis ... See more keywords
Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis
Sign Up to like & getrecommendations! Published in 2018 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2018.1512521
Abstract: ABSTRACT Here, we investigated the possible anti-cancer properties of bromelain in Kras mutant human colorectal carcinoma cell lines and a mouse model harboring a Kras mutation. Cell growth and proliferation were significantly reduced in the… read more here.
Keywords: mutant colorectal; bromelain; colorectal cancer; kras mutant ... See more keywords
Effect of Oral Administration of Bromelain on Postoperative Discomfort After Third Molar Surgery
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Craniofacial Surgery"
DOI: 10.1097/scs.0000000000003154
Abstract: Introduction: The purpose of this prospective randomized controlled clinical trial was to evaluate the effect of oral administration of bromelain on discomfort after mandibular third molar surgery. Materials and Methods: Eighty-four consecutive patients requiring surgical… read more here.
Keywords: control group; bromelain; group; third molar ... See more keywords
Purification and characterization of bromelain from pineapple (Ananas comosus L.) peel waste.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of food science"
DOI: 10.1111/1750-3841.15563
Abstract: Bromelain is widely used in food industry and pharmaceutical products due to its strong antioxidant properties. Therefore, the extraction of bromelain from pineapple peel may improve the profitability and sustainability of pineapple industry. The aim… read more here.
Keywords: bromelain pineapple; purification characterization; pineapple peel; bromelain ... See more keywords