Bromo-lactamization of isoxazole via neighboring group participation: toward spiro-isoxazoline γ- and δ-lactams
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DOI: 10.1039/d2ra01070d
Abstract: Spiro-heterocycles containing natural products and synthetic analogues have a broader biomedicinal application due to their rigid 3D conformation and structural implications. In this context, constructing spiro-isoxazoline systems have continued our interest in natural products and… read more here.
Keywords: neighboring group; bromo lactamization; isoxazoline lactams; group participation ... See more keywords