Nickel-Catalyzed Chemo- and Regioselective Benzylarylation of Unactivated Alkenes with o-Bromobenzyl Chlorides.
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DOI: 10.1021/acs.orglett.1c03991
Abstract: Chemo- and regioselectively nickel-catalyzed reductive benzylarylation of unactivated alkenes with o-bromobenzyl chlorides is disclosed herein, in which electrophiles participate through a single-component double-site approach. Moreover, its utility is underscored by the concise synthesis of bioactive… read more here.
Keywords: nickel catalyzed; chemo; benzylarylation unactivated; unactivated alkenes ... See more keywords