Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins.
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DOI: 10.1021/acs.jmedchem.7b00611
Abstract: The bromodomain and plant homeodomain finger-containing (BRPF) family are scaffolding proteins important for the recruitment of histone acetyltransferases of the MYST family to chromatin. Here, we describe NI-57 (16) as new pan-BRPF chemical probe of… read more here.
Keywords: plant homeodomain; finger containing; bromodomain plant; family ... See more keywords