Cyclization and oxidation of o-bromophenylacetamides for the synthesis of oxindoles and isoindigoes
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DOI: 10.1016/j.tet.2017.12.005
Abstract: Abstract N-substituted oxindoles were obtained through a facile KOH/DMSO promoted intramolecular cyclization of o-bromophenylacetamides in good yields. Furthermore, isoindigo derivatives were readily synthesized through sequential intramolecular cyclization, oxidation and condensation of o-bromophenylacetamide in the presence… read more here.
Keywords: oxidation bromophenylacetamides; bromophenylacetamides synthesis; cyclization; cyclization oxidation ... See more keywords