Misregulation of bromotyrosine compromises fertility in male Drosophila
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DOI: 10.1073/pnas.2322501121
Abstract: Significance The biological significance of halogenation and dehalogenation are well illustrated by the hormone thyroxine and the extent to which biology depends on these types of reactions is more general than first anticipated. The ubiquity… read more here.
Keywords: misregulation bromotyrosine; compromises fertility; bromotyrosine compromises; dehalogenation ... See more keywords
Presence of Bromotyrosine Alkaloids in Marine Sponges Is Independent of Metabolomic and Microbiome Architectures
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DOI: 10.1128/msystems.01387-20
Abstract: Our work demonstrates that phylogenetically and geographically distant sponges with very different microbiomes can harbor natural product chemical classes that are united in their core chemical structures and biosynthetic logic. Furthermore, we show that independent… read more here.
Keywords: microbiome; bromotyrosine; bromotyrosine alkaloids; natural product ... See more keywords
Marine Bromotyrosine Derivatives in Spotlight: Bringing Discoveries and Biological Significance
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DOI: 10.3390/md22030132
Abstract: The Verongida order comprises several sponge families, such as Aplysinellidae, Aplysinidae, Ianthellidae, and Pseudoceratinidae, reported for producing bromotyrosine-derived compounds. First identified in 1913, bromotyrosine derivatives have since captivated interest notably for their antitumor and antimicrobial… read more here.
Keywords: bromotyrosine derivatives; bringing discoveries; spotlight bringing; marine bromotyrosine ... See more keywords
Using UHPLC–MS profiling for the discovery of new sponge-derived metabolites and anthelmintic screening of the NatureBank bromotyrosine library
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DOI: 10.3762/bjoc.18.164
Abstract: In order to further expand the NatureBank open access compound library, chemical investigations of the Australian marine sponge, Ianthella basta, were undertaken since UHPLC–MS analysis of the extract from this sponge indicated the presence of… read more here.
Keywords: bromotyrosine; library; using uhplc; profiling discovery ... See more keywords