5-Chlorouracil and 5-bromouracil acid-base equilibrium study in water and DMSO by NMR spectroscopy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.01.013
Abstract: Abstract Mechanism of 5-chloro- and 5-bromouracil deprotonation in water and dimethyl sulfoxide (DMSO) has been studied by the 13C and 1H NMR spectroscopy. NMR spectra were interpreted using DFT quantum chemical calculations at the CSGT-PCM-TPSSTPSS/6-311+G(d,… read more here.
Keywords: water; nmr spectroscopy; bromouracil; spectroscopy ... See more keywords
Insights into the deactivation of 5-bromouracil after ultraviolet excitation
Sign Up to like & getrecommendations! Published in 2017 at "Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences"
DOI: 10.1098/rsta.2016.0202
Abstract: 5-Bromouracil is a nucleobase analogue that can replace thymine in DNA strands and acts as a strong radiosensitizer, with potential applications in molecular biology and cancer therapy. Here, the deactivation of 5-bromouracil after ultraviolet irradiation… read more here.
Keywords: state; deactivation; bromouracil; insights deactivation ... See more keywords