In vitro long‐term repeated exposure and exposure switching of a novel tobacco vapor product in a human organotypic culture of bronchial epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3982
Abstract: Abstract Next‐generation tobacco products and nicotine delivery systems such as heat‐not‐burn tobacco products and electronic cigarettes, the usage of which is expected to have a beneficial impact on public health, have gained popularity over the… read more here.
Keywords: tobacco; repeated exposure; long term; product ... See more keywords
Toxicity of iron nanoparticles towards primary cultures of human bronchial epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4033
Abstract: Air pollution is a public health issue and the toxicity of ambient particulate matter (PM) is well‐recognized. Although it does not mostly contribute to the total mass of PM, increasing evidence indicates that the ultrafine… read more here.
Keywords: epithelial cells; toxicity iron; toxicity; bronchial epithelial ... See more keywords
Evaluation of chronic cigarette smoke exposure in human bronchial epithelial cultures
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4430
Abstract: Cigarette smoke (CS) exposure induces both cytotoxicity and inflammation, and often causes COPD, a growing cause of morbidity and mortality. CS also inhibits the CFTR Cl‐ channel, leading to airway surface liquid dehydration, which is… read more here.
Keywords: exposure; cigarette smoke; bronchial epithelial; epithelial cultures ... See more keywords
Identification of apoptosis‐associated protein factors distinctly expressed in cigarette smoke condensate‐exposed airway bronchial epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22444
Abstract: Smoking is associated with an increased risk of respiratory diseases, including lung cancer and asthma. However, the mechanisms or diagnostic markers for smoking‐related diseases remain largely unknown. Here we investigated the role of cigarette smoke… read more here.
Keywords: epithelial cells; apoptosis; protein factors; cigarette smoke ... See more keywords
The toxicity of cooking oil fumes on human bronchial epithelial cells through ROS‐mediated MAPK, NF‐κB signaling pathways and NLRP3 inflammasome
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23465
Abstract: Cooking oil fumes (COFs) are the main pollutants in kitchen and indoor air, which threaten human health. Exposure to COFs may lead to respiratory diseases and impair pulmonary function. To investigate the toxicity of COFs… read more here.
Keywords: mapk signaling; cooking oil; toxicity; human bronchial ... See more keywords
Polystyrene microplastic particles induce autophagic cell death in BEAS‐2B human bronchial epithelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23705
Abstract: The detection of high levels of microplastics in indoor and outdoor air has increased concerns regarding its toxic effects on the respiratory system. They are not easily degradable and can be deposited deep in the… read more here.
Keywords: cell death; autophagic cell; bronchial epithelial; epithelial cells ... See more keywords
Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCHL1 suppresses epithelial-mesenchymal transition and is under-expressed in cadmium-transformed human bronchial epithelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cell biology and toxicology"
DOI: 10.1007/s10565-020-09560-2
Abstract: Cadmium (Cd), a highly toxic heavy metal, is widespreadly distributed in the environment. Chronic exposure to Cd is associated with the development of several diseases including cancers. Over the decade, many researches have been carried… read more here.
Keywords: epithelial cells; mesenchymal transition; transition; bronchial epithelial ... See more keywords
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0674-6
Abstract: The nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3) inflammasome has developed as an important bridge between innate immune and infection recently, and has the ability to drive proteolytic procaspase-1 into bioactive caspase-1, then responsible… read more here.
Keywords: epithelial cells; fungal glucan; bronchial epithelial; human bronchial ... See more keywords
Cryptococcus neoformans in Association with Dermatophagoides pteronyssinus has Pro- (IL-6/STAT3 Overproduction) and Anti-inflammatory (CCL2/ERK1/2 Downregulation) Effects on Human Bronchial Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Inflammation"
DOI: 10.1007/s10753-021-01619-4
Abstract: Cryptococcosis (caused, for example, by Cryptococcus neoformans ) and allergic asthma (caused, for example, by Dermatophagoides pteronyssinus ) target the respiratory tract (the lung and bronchial epithelium). C. neoformans and D. pteronyssinus can coexist in… read more here.
Keywords: dermatophagoides pteronyssinus; human bronchial; cryptococcus neoformans; ccl2 ... See more keywords
The differential effects of commercial specialized media on cell growth and transforming growth factor beta 1-induced epithelial-mesenchymal transition in bronchial epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05439-x
Abstract: Epithelial-mesenchymal transition (EMT) is one of the mechanisms that contribute to bronchial remodelling which underlie chronic inflammatory airway diseases such as chronic obstructive pulmonary disorder (COPD) and asthma. Bronchial EMT can be triggered by many… read more here.
Keywords: emt; cell growth; bronchial epithelial; factor ... See more keywords
Porphyromonas gingivalis Mfa1 fimbria putatively binds to TLR2 and induces both IL-6 and IL-8 production in human bronchial epithelial cells.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.12.003
Abstract: Porphyromonas gingivalis (Pg) a major periodontal pathogen involved in periodontal disease development and progression. Moreover, Pg has two fimbriae surface proteins (FimA and Mfa1) that are genetically distinct and make-up the fimbrial shaft which in-turn… read more here.
Keywords: functional response; porphyromonas gingivalis; human bronchial; bronchial epithelial ... See more keywords