Hydrogen sulfide inhibits apoptosis and protects the bronchial epithelium in an allergic inflammation mice model.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.05.041
Abstract: Studies suggest that hydrogen sulfide (H2S) plays a relevant and beneficial role in the pathophysiology of pulmonary allergic diseases, such as asthma. These diseases may be triggered by changes in airway epithelium caused by repeated… read more here.
Keywords: apoptosis; protects bronchial; epithelium; mice ... See more keywords
Bronchial epithelium repair by Esculentin-1a-derived antimicrobial peptides: involvement of metalloproteinase-9 and interleukin-8, and evaluation of peptides’ immunogenicity
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55426-x
Abstract: The airway epithelium is seriously damaged upon pulmonary Pseudomonas aeruginosa infection, especially in cystic fibrosis (CF) sufferers. Therefore, the discovery of novel anti-infective agents accelerating healing of infected injured tissues is crucial. The antipseudomonal peptides… read more here.
Keywords: epithelium repair; epithelium; metalloproteinase; esc peptides ... See more keywords
Long-term evolution of the epithelial cell secretome in preclinical 3D models of the human bronchial epithelium
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-86037-0
Abstract: The human bronchial epithelium is the first line of defense against atmospheric particles, pollutants, and respiratory pathogens such as the novel SARS-CoV-2. The epithelial cells form a tight barrier and secrete proteins that are major… read more here.
Keywords: epithelial cell; long term; epithelium; human bronchial ... See more keywords
112 Use of a Human Bronchial Epithelium Model to Assess the Impact of PM2.5 Exposure on the Severity of Viral Infections
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Work Exposures and Health"
DOI: 10.1093/annweh/wxac087.157
Abstract: Epidemiological studies have shown an association between exposure to fine particles (PM2.5) and the severity of respiratory infections such as influenza and COVID-19. PM2.5 and viruses target the bronchial epithelium suggesting that exposure to PM2.5… read more here.
Keywords: severity viral; bronchial epithelium; exposure; pm2 ... See more keywords
Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.768770
Abstract: Aim: Whether accelerated aging, reflected by sirtuin 1 (SIRT1) expression, is implicated in bronchiectasis remains largely unknown. We sought to determine the patterns of SIRT1 and other aging markers in systemic circulation and airways and… read more here.
Keywords: expression; bronchiectasis; patients bronchiectasis; systemic circulation ... See more keywords
An impact of age on respiratory syncytial virus infection in air-liquid-interface culture bronchial epithelium
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1144050
Abstract: Background Elderly people are known to be vulnerable to virus infection. However, this has not been appropriately tested in in vitro studies due to a lack of appropriate virus infection models. In this report, we… read more here.
Keywords: virus infection; viral load; age; bronchial epithelium ... See more keywords
SIRT3 regulates bronchial epithelium apoptosis and aggravates airway inflammation in asthma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2022.12660
Abstract: Sirtuin (SIRT)3 is closely related to inflammation and apoptosis and studies have described this relationship, including in the lungs. However, the expression of SIRT3 and its effect on apoptosis and inflammation in bronchial tissue in… read more here.
Keywords: inflammation; apoptosis; sirt3; expression ... See more keywords