Assessment of airway inflammation and remodeling in children with severe asthma: The next challenge
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24051
Abstract: Severe Asthma (SA) in children is relatively rare, affecting 2-5% of the asthmatic pediatric population. However, its burden is disproportionally high, as children with SA experience frequent asthma attacks, have a reduced quality of life,… read more here.
Keywords: inflammation remodeling; inflammation; airway inflammation; bronchial mucosa ... See more keywords
Development of Combining of Human Bronchial Mucosa Models with XposeALI® for Exposure of Air Pollution Nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0170428
Abstract: Background Exposure to agents via inhalation is of great concerns both in workplace environment and in the daily contact with particles in the ambient air. Reliable human airway exposure systems will most likely replace animal… read more here.
Keywords: microscopy; exposure; air; human bronchial ... See more keywords
Establishment of Repeated In Vitro Exposure System for Evaluating Pulmonary Toxicity of Representative Criteria Air Pollutants Using Advanced Bronchial Mucosa Models
Sign Up to like & getrecommendations! Published in 2022 at "Toxics"
DOI: 10.3390/toxics10060277
Abstract: There is mounting evidence that shows the association between chronic exposure to air pollutants (particulate matter and gaseous) and onset of various respiratory impairments. However, the corresponding toxicological mechanisms of mixed exposure are poorly understood.… read more here.
Keywords: air pollutants; evaluating pulmonary; bronchial mucosa; air ... See more keywords
Levels of CD4+ CD25+ T regulatory cells in bronchial mucosa and peripheral blood of chronic obstructive pulmonary disease indicate involvement of autoimmunity mechanisms.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in respiratory medicine"
DOI: 10.5603/arm.2019.0023
Abstract: INTRODUCTION Many theories have been proposed to explain pathogenesis of COPD; however, remains unclear why the majority of smokers (~80%) do not develop COPD, or only develop a mild disease. To explore if COPD has… read more here.
Keywords: cd4 cd25; peripheral blood; bronchial mucosa; copd ... See more keywords