Bronchial smooth muscle cell in asthma: where does it fit?
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DOI: 10.1136/bmjresp-2022-001351
Abstract: Asthma is a frequent respiratory condition whose pathophysiology relies on altered interactions between bronchial epithelium, smooth muscle cells (SMC) and immune responses. Those leads to classical hallmarks of asthma: airway hyper-responsiveness, bronchial remodelling and chronic… read more here.
Keywords: bronchial smooth; muscle cell; muscle; bronchial remodelling ... See more keywords
Crucial role of fatty acid oxidation in asthmatic bronchial smooth muscle remodelling
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DOI: 10.1183/13993003.04252-2020
Abstract: Background Bronchial smooth muscle (BSM) remodelling in asthma is related to an increased mitochondrial biogenesis and enhanced BSM cell proliferation in asthma. Since mitochondria produce the highest levels of cellular energy and fatty acid β-oxidation… read more here.
Keywords: oxidation; asthmatic bsm; bsm; fatty acid ... See more keywords
Prostaglandin D2 Induces Ca2+ Sensitization of Contraction without Affecting Cytosolic Ca2+ Level in Bronchial Smooth Muscle
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DOI: 10.3390/ijms19103036
Abstract: Prostaglandin D2 (PGD2) is one of the key lipid mediators of allergic airway inflammation, including bronchial asthma. However, the role of PGD2 in the pathogenesis of asthma is not fully understood. In the present study,… read more here.
Keywords: bronchial smooth; contraction; smooth muscle; cytosolic ca2 ... See more keywords