Anti-inflammatory and bronchodilatory constituents of leaf extracts of Anacardium occidentale L. in animal models.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of integrative medicine"
DOI: 10.1016/j.joim.2017.12.009
Abstract: OBJECTIVE Anacardium occidentale L. leaf is useful in the treatment of inflammation and asthma, but the bioactive constituents responsible for these activities have not been characterized. Therefore, this study was aimed at identifying the bioactive… read more here.
Keywords: anti inflammatory; bronchodilatory anti; bronchoconstriction; bronchodilatory ... See more keywords
Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyperresponsiveness
Sign Up to like & getrecommendations! Published in 2018 at "Nature neuroscience"
DOI: 10.1038/s41593-018-0074-8
Abstract: Asthma, accompanied by lung inflammation, bronchoconstriction and airway hyper-responsiveness, is a significant public health burden. Here we report that Mas-related G protein-coupled receptors (Mrgprs) are expressed in a subset of vagal sensory neurons innervating the… read more here.
Keywords: mrgprs vagal; neurons contribute; bronchoconstriction airway; bronchoconstriction ... See more keywords
Breathing pattern changes in response to bronchoconstriction in physically active adults
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Asthma"
DOI: 10.1080/02770903.2024.2383632
Abstract: Abstract Objectives To determine whether Opto-Electronic Plethysmography (OEP) can distinguish Exercise-Induced Bronchoconstriction (EIB) breathing patterns by comparing individuals with and without EIB, and between broncho-constriction and recovery. Breathing pattern was quantified in terms of regional… read more here.
Keywords: bronchoconstriction; breathing pattern; post; eib ... See more keywords
Effect of Bronchoconstriction-induced Ventilation–Perfusion Mismatch on Uptake and Elimination of Isoflurane and Desflurane
Sign Up to like & getrecommendations! Published in 2017 at "Anesthesiology"
DOI: 10.1097/aln.0000000000001847
Abstract: Background: Increasing numbers of patients with obstructive lung diseases need anesthesia for surgery. These conditions are associated with pulmonary ventilation/perfusion (VA/Q) mismatch affecting kinetics of volatile anesthetics. Pure shunt might delay uptake of less soluble… read more here.
Keywords: bronchoconstriction; uptake elimination; isoflurane; elimination ... See more keywords
Bronchoconstriction damages airway epithelia by crowding-induced excess cell extrusion
Sign Up to like & getrecommendations! Published in 2024 at "Science"
DOI: 10.1126/science.adk2758
Abstract: Asthma is deemed an inflammatory disease, yet the defining diagnostic feature is mechanical bronchoconstriction. We previously discovered a conserved process called cell extrusion that drives homeostatic epithelial cell death when cells become too crowded. In… read more here.
Keywords: bronchoconstriction; crowding induced; cell; cell extrusion ... See more keywords
Mitigation of airways responsiveness by deep inflation of the lung.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00051.2018
Abstract: Stretching activated strips of airway smooth muscle (ASM) significantly affects both active force and stiffness due to a temporary reduction of the proportion of cycling myosin cross bridges that are bound to their actin binding… read more here.
Keywords: inflation lung; deep inflation; bronchoconstriction; airways responsiveness ... See more keywords
Hypoxic Pulmonary Vasoconstriction Does Not Explain All Regional Perfusion Redistribution in Asthma
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201612-2438oc
Abstract: Rationale: Regional hypoventilation in bronchoconstricted patients with asthma is spatially associated with reduced perfusion, which is proposed to result from hypoxic pulmonary vasoconstriction (HPV). Objectives: To determine the role of HPV in the regional perfusion… read more here.
Keywords: perfusion; perfusion redistribution; bronchoconstriction; hypoxic pulmonary ... See more keywords
Communications between Pulmonary Airways and Blood Vessels. A New Mechanism?
Sign Up to like & getrecommendations! Published in 2017 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.201706-1260ed
Abstract: Hypoxic pulmonary vasoconstriction (HPV) is believed to play an important homeostatic role in asthma and other heterogeneous lung diseases by redistributing blood flow from regions that are relatively poorly ventilated, and thus hypoxic, to those… read more here.
Keywords: perfusion; bronchoconstriction; hpv; blood ... See more keywords
Bronchoconstriction Induced by Spirometric Maneuvers in a Male Patient: A Case Report
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DOI: 10.1177/15579883251339559
Abstract: Spirometry-induced bronchoconstriction (SIB) refers to the paradoxical narrowing of the airways triggered by deep inhalation (DI) during spirometry testing. This response is atypical but can occur in subjects with heightened airway sensitivity, such as those… read more here.
Keywords: bronchoconstriction; male patient; case report; spirometric maneuvers ... See more keywords
Exercise-Induced Bronchoconstriction in Children
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.814976
Abstract: Exercise-induced bronchoconstriction (EIB) is a transient airflow obstruction, typically 5–15 min after physical activity. The pathophysiology of EIB is related to the thermal and osmotic changes of the bronchial mucosa, which cause the release of… read more here.
Keywords: bronchoconstriction; bronchoconstriction children; exercise induced; induced bronchoconstriction ... See more keywords
Vagus nerve stimulation as a potential treatment for acute asthmatic bronchoconstriction: a systematic review
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2025.1625871
Abstract: Objective Vagus nerve stimulation (VNS) is a therapeutic option for diseases such as epilepsy and depression. Given that the smooth muscle of the bronchi is innervated by the vagus nerve, VNS could aid in treating… read more here.
Keywords: vagus nerve; bronchoconstriction; review; vns ... See more keywords