Dual bronchodilation for the treatment of COPD: From bench to bedside
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15390
Abstract: Because there is a solid pharmacological rationale based on positive interactions between long‐acting muscarinic receptor antagonists (LAMAs) and long‐acting β‐agonists (LABAs) for their ability to relax human airway smooth muscle in vitro alongside several randomised… read more here.
Keywords: bronchodilation; copd; laba fdcs; lama laba ... See more keywords
Field-applicable low-intensity exercise induces bronchodilation in horses with severe asthma.
Sign Up to like & getrecommendations! Published in 2025 at "Equine veterinary journal"
DOI: 10.1111/evj.70111
Abstract: BACKGROUND Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise-induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter,… read more here.
Keywords: bronchodilation; exercise; sea; lung function ... See more keywords
The Respiratory “Overlap Syndrome”: Efficacy and Usefulness of the Combined Double Bronchodilation
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DOI: 10.1159/000487179
Abstract: The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome in a single patient is known as “overlap syndrome,” and worsens the prognosis of the affected subjects. A marked bronchodilation may be… read more here.
Keywords: syndrome efficacy; overlap syndrome; respiratory overlap; bronchodilation ... See more keywords
Piezo1 Agonist Yoda1 Induces Rapid Relaxation in Cultured Airway Smooth Muscle Cells and Bronchodilation in Mouse Models.
Sign Up to like & getrecommendations! Published in 2025 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2024-0536oc
Abstract: Bronchodilators that relax airway smooth muscle cells (ASMCs) are essential for treating constrictive airway diseases such as asthma. However, the existing bronchodilators are often unable to control symptoms of severe asthmatic patients, leaving a pressing… read more here.
Keywords: agonist yoda1; mouse models; airway smooth; relaxation ... See more keywords
The future of bronchodilation: looking for new classes of bronchodilators
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DOI: 10.1183/16000617.0095-2019
Abstract: Available bronchodilators can satisfy many of the needs of patients suffering from airway disorders, but they often do not relieve symptoms and their long-term use raises safety concerns. Therefore, there is interest in developing new… read more here.
Keywords: future bronchodilation; classes bronchodilators; receptor agonists; bronchodilation ... See more keywords