An epistatic interaction between pre-natal smoke exposure and socioeconomic status has a significant impact on bronchodilator drug response in African American youth with asthma
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DOI: 10.1186/s13040-020-00218-7
Abstract: Background Asthma is one of the leading chronic illnesses among children in the United States. Asthma prevalence is higher among African Americans (11.2%) compared to European Americans (7.7%). Bronchodilator medications are part of the first-line… read more here.
Keywords: bdr; american youth; drug response; bronchodilator drug ... See more keywords
Epigenome-Wide Association Studies of the Fractional Exhaled Nitric Oxide and Bronchodilator Drug Response in Moderate-to-Severe Pediatric Asthma
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DOI: 10.3390/biomedicines11030676
Abstract: Asthma is the most prevalent pediatric chronic disease. Bronchodilator drug response (BDR) and fractional exhaled nitric oxide (FeNO) are clinical biomarkers of asthma. Although DNA methylation (DNAm) contributes to asthma pathogenesis, the influence of DNAm… read more here.
Keywords: bdr; exhaled nitric; asthma; drug response ... See more keywords