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   Articles with "bronj" as a keyword



Zoledronic Acid Regulates Osteoclasts via miR‐483‐5p in the BRONJ

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recommendations! Published in 2025 at "Oral Diseases"

DOI: 10.1111/odi.15233

Abstract: Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a severe complication of bisphosphonate therapy, with unclear mechanisms. This study investigates the regulatory impact of zoledronic acid (ZOL) on osteoclasts and microRNA (miRNA) expression. read more here.

Keywords: regulates osteoclasts; bronj; osteoclasts via; acid regulates ... See more keywords

Database analysis of the risk factors of bisphosphonate-related osteonecrosis of the jaw in Hungarian patients

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recommendations! Published in 2019 at "BMJ Open"

DOI: 10.1136/bmjopen-2018-025600

Abstract: Objective Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare but serious side effect of bisphosphonates (BPs). Since this disease has no independent code in either of the diseases’ or in the medical procedures’ classifications,… read more here.

Keywords: osteonecrosis; risk; related osteonecrosis; bronj ... See more keywords

Bioinformatic Data Mining for Candidate Drugs Affecting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) in Cancer Patients

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recommendations! Published in 2022 at "Disease Markers"

DOI: 10.1155/2022/3348480

Abstract: Background Bisphosphonate-related osteonecrosis of the jaw (BRONJ) leads to significant morbidity. Other coadministered drugs may modulate the risk for BRONJ. The present study aimed to leverage bioinformatic data mining to identify drugs that potentially modulate… read more here.

Keywords: bronj cancer; bioinformatic data; bronj; risk ... See more keywords

Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy

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recommendations! Published in 2025 at "Journal of Nanobiotechnology"

DOI: 10.1186/s12951-025-03745-9

Abstract: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe, therapy-refractory condition driven by ferroptotic disruption of jawbone-derived mesenchymal stem cells (MSCs) biology. We dissect this mechanism to validate ferroptosis as a therapeutic target. We first… read more here.

Keywords: bronj; therapy; ferroptosis; jawbone ... See more keywords