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Published in 2022 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3594
Abstract: Approximately 30% of the global population is affected by obesity. Traditional non‐surgical measures for weight loss have limited efficacy and tolerability. Therefore, there is a need for novel, effective therapies. Brown adipose tissue (BAT) has…
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Keywords:
regulation human;
brown adipose;
adipose tissue;
human body ... See more keywords
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1
Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12881
Abstract: Brown adipose tissue (BAT) has been primarily researched as a potential target for mitigating obesity. However, the physiological significance of BAT in relation to cachexia remains poorly understood. The objective of this study was to…
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Keywords:
obstructive pulmonary;
emphysematous chronic;
chronic obstructive;
adipose tissue ... See more keywords
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Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25364
Abstract: To evaluate the volume and changes of human brown adipose tissue (BAT) in vivo following exposure to cold using magnetic resonance imaging (MRI).
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Keywords:
cold stimulation;
adipose tissue;
vivo assessment;
assessment cold ... See more keywords
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Published in 2022 at "Lipids"
DOI: 10.1002/lipd.12358
Abstract: Although it is well established that glucocorticoids inactivate thermogenesis and promote lipid accumulation in interscapular brown adipose tissue (IBAT), the underlying mechanisms remain unknown. We found that dexamethasone treatment (1 mg/kg) for 7 days in rats decreased…
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Keywords:
glycerol;
adipose tissue;
triacylglycerol;
activity ... See more keywords
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Published in 2023 at "Magnetic resonance in medicine"
DOI: 10.1002/mrm.29707
Abstract: PURPOSE Activated brown adipose tissue (BAT) enhances lipid catabolism and improves cardiometabolic health. Quantitative MRI of the fat fraction (FF) of supraclavicular BAT (scBAT) is a promising noninvasive measure to assess BAT activity but suffers…
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Keywords:
variability;
mri;
brown adipose;
mutual thresholding ... See more keywords
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Published in 2018 at "Obesity"
DOI: 10.1002/oby.22062
Abstract: Human brown adipose tissue (BAT) activity decreases with age and obesity. In addition to uncoupling protein 1 (UCP1), several genetic markers of BAT in humans have been published. However, the link between human BAT activity…
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Keywords:
adipose tissue;
genetic markers;
markers brown;
activity ... See more keywords
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Published in 2020 at "Obesity"
DOI: 10.1002/oby.22698
Abstract: This study aimed to quantify and compare the amount, activity, and anatomical distribution of cold‐activated brown adipose tissue (BAT) in healthy, young, lean women and men.
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Keywords:
dimorphisms adult;
adult human;
sexual dimorphisms;
adipose tissue ... See more keywords
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Published in 2019 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2018_123
Abstract: Brite/brown adipose tissue (BAT) is a thermogenic tissue able to dissipate energy via non-shivering thermogenesis. It is naturally activated by cold and has been demonstrated to increase thermogenic capacity, elevate energy expenditure, and to ultimately…
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Keywords:
regulatory small;
tissue;
brite brown;
noncoding rnas ... See more keywords
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Published in 2019 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2018_137
Abstract: Historically, brown adipose tissue has been elusive and not easy to detect, hence its relative obscurity in human physiology until its rediscovery in 2009. At that point, it was proven that the symmetrical artefacts frequently…
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Keywords:
physiology;
infrared thermography;
adipose tissue;
brown adipose ... See more keywords
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Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-70178-3_15
Abstract: Physiologically, estrogens carry out a myriad of functions, the most essential being the regulation of the reproductive axis. Currently, it is also dogmatic that estrogens play an important role modulating energy balance and metabolism. In…
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Keywords:
energy;
adipose tissue;
regulation;
thermogenesis ... See more keywords
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Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03046-z
Abstract: RDH1 is one of the several enzymes that catalyze the first of the two reactions to convert retinol into all-trans-retinoic acid (atRA). Here, we show that Rdh1-null mice fed a low-fat diet gain more weight…
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Keywords:
rdh1;
fasting feeding;
adiposity;
bat ... See more keywords