Brown and Beige Adipose Tissues in Health and Disease.
Sign Up to like & getrecommendations! Published in 2017 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c170001
Abstract: Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue (BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat develops postnatally and is highly inducible. Beige fat recruitment is… read more here.
Keywords: bat beige; beige adipocytes; beige fat; beige ... See more keywords
In vivo metabolic imaging and monitoring of brown and beige fat.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201800019
Abstract: Activation of the thermogenic brown and beige fat is an effective means to increasing whole-body energy expenditure. In this work, a unique label-free method was developed to quantitatively assess the metabolism and thermogenesis of mouse… read more here.
Keywords: imaging monitoring; beige fat; brown beige; monitoring brown ... See more keywords
Dynamic contrast‐enhanced MRI of brown and beige adipose tissues
Sign Up to like & getrecommendations! Published in 2019 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.28118
Abstract: The vascular blood flow in brown adipose tissue (BAT) is important for handling triglyceride clearance, increased blood flow and oxygenation. We used dynamic contrast‐enhanced (DCE)‐MRI and fat fraction (FF) imaging for investigating vascular perfusion kinetics… read more here.
Keywords: beige adipose; adipose tissues; brown beige; dynamic contrast ... See more keywords
Emerging Role of AMPK in Brown and Beige Adipose Tissue (BAT): Implications for Obesity, Insulin Resistance, and Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Current Diabetes Reports"
DOI: 10.1007/s11892-018-1049-6
Abstract: Purpose of ReviewThe global prevalence of type 2 diabetes (T2D) is escalating at alarming rates, demanding the development of additional classes of therapeutics to further reduce the burden of disease. Recent studies have indicated that… read more here.
Keywords: beige adipose; tissue; ampk; brown beige ... See more keywords
Nutritional and metabolic regulation of brown and beige adipose tissues
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-020-00745-1
Abstract: The last decade has witnessed an enormous interest of scientists and clinicians in the understanding of the biological activity of brown adipose tissue (BAT) and its role in health and disease. The importance of BAT… read more here.
Keywords: bat; beige adipose; brown beige; brown adipocytes ... See more keywords
Cold-Inducible SIRT6 Regulates Thermogenesis of Brown and Beige Fat.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.06.069
Abstract: Promoting development and function of brown and beige fat may reduce obesity. Here, we show that fat SIRT6 expression is markedly induced by cold exposure and a β-adrenergic agonist. Deletion of SIRT6 in adipose tissue… read more here.
Keywords: inducible sirt6; beige fat; fat; brown beige ... See more keywords
FGF2 disruption enhances thermogenesis in brown and beige fat to protect against adiposity and hepatic steatosis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2021.101358
Abstract: Objective Fibroblast growth factor 2 (FGF2) has been reported to play divergent roles in white adipogenic differentiation, however, whether it regulates thermogenesis of fat tissues remains largely unknown. We therefore aimed to investigate the effect… read more here.
Keywords: hepatic steatosis; fgf2; adiposity; fat ... See more keywords
Transcriptional and epigenetic control of brown and beige adipose cell fate and function
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/nrm.2017.72
Abstract: | White adipocytes store excess energy in the form of triglycerides, whereas brown and beige adipocytes dissipate energy in the form of heat. This thermogenic function relies on the activation of brown and beige adipocyte-specific… read more here.
Keywords: brown beige; adipose cell; biology; cell fate ... See more keywords
UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00498
Abstract: Mammals have two types of thermogenic adipocytes: brown adipocytes and beige adipocytes. Thermogenic adipocytes express high levels of uncoupling protein 1 (UCP1) to dissipates energy in the form of heat by uncoupling the mitochondrial proton… read more here.
Keywords: beige adipocytes; thermogenic adipocytes; ucp1 dependent; brown beige ... See more keywords
Econutrition, brown and beige fat tissue and obesity.
Sign Up to like & getrecommendations! Published in 2020 at "Asia Pacific journal of clinical nutrition"
DOI: 10.6133/apjcn.202012_29(4).0001
Abstract: BACKGROUND AND OBJECTIVES Obesity is caused by excessive fat accumulation or abnormal fat distribution and has become one of the biggest health challenges worldwide. Considering the high thermogenic ability of brown fat tissue (BAT) and… read more here.
Keywords: fat tissue; bat; brown beige; econutrition brown ... See more keywords
Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.63067
Abstract: Obesity, a metabolic disease caused by multiple factors, has become a global health problem. In addition to nutrient intake and sedentary lifestyle, environmental pollutants exposure has been shown to be involved in obesity epidemics. Antibiotics,… read more here.
Keywords: brown beige; obesity; beige adipocytes; azithromycin inhibits ... See more keywords