Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3741
Abstract: Nitrate, a nitric oxide (NO) donor, has antiobesity effect in female rats. This study hypothesized that the antiobesity effect of nitrate in female rats is due to the browning of white adipose tissue (WAT). Female… read more here.
Keywords: female rats; adipose tissue; tissue; browning white ... See more keywords
Loss of cytoplasmic FMR1‐interacting protein 2 (CYFIP2) induces browning in 3T3‐L1 adipocytes via repression of GABA‐BR and activation of mTORC1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30231
Abstract: Obesity and related metabolic disorders are epidemic diseases. Promoting thermogenesis and a functional increase in the browning of white adipocytes may counteract obesity. On the other hand, the molecular mechanism that regulates brown and beige… read more here.
Keywords: cyfip2; cyfip2 induces; white adipocytes; loss ... See more keywords
Reversine promotes browning of white adipocytes by suppressing miR‐133a
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27148
Abstract: Brown adipocytes are characterized by a high number of uncoupling protein 1 (UCP1)‐positive mitochondrial content and increased thermogenic capacity. As UCP1‐enriched cells can consume lipids by generating heat, browning of white adipocytes is now highlighted… read more here.
Keywords: 133a reversine; white adipocytes; mir 133a; browning white ... See more keywords
Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes
Sign Up to like & getrecommendations! Published in 2020 at "Protein & Cell"
DOI: 10.1007/s13238-020-00717-7
Abstract: Obesity is caused by an imbalance between energy intake and expenditure, and has become a global epidemic with over 650 million adults affected. Adipose tissues in mammals are composed of white adipose tissue (WAT) and… read more here.
Keywords: white adipocytes; beige adipocytes; obesity; ethacrynic acid ... See more keywords
SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110408
Abstract: The adipose tissue is a key site regulating energy metabolism. One of the contributing factors behind this is browning of white adipose tissue (WAT). However, knowledge of the intracellular determinants of the browning process remains… read more here.
Keywords: ebp senp2; senp2 suppresses; browning white; senp2 ... See more keywords
Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/ijo.2017.208
Abstract: Aims:The objective of this study is to characterize the relationship between forkhead box C2 protein (Foxc2) and leptin under adipose inflammatory response.Methods:Lipopolysaccharide (LPS)-induced inflammatory model was conducted. Data from wild-type and ob/ob mice were used… read more here.
Keywords: leptin; inflammation; white adipose; foxc2 ... See more keywords
Compromised browning in white adipose tissue of aging people.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of endocrinology"
DOI: 10.1093/ejendo/lvad014
Abstract: BACKGROUND Adipose tissue plays a pivotal role in pathology of metabolic disorders. In the past decade brown and brown-like adipose tissue were detected in adult human and show therapeutic potential in aging-related metabolic diseases. OBJECTIVE… read more here.
Keywords: adipose tissue; compromised browning; white adipose; browning white ... See more keywords
Alternatively Activated Macrophages Drive Browning of White Adipose Tissue in Burns
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Surgery"
DOI: 10.1097/sla.0000000000002465
Abstract: Objective: The aim of this study was to uncover the mediators and mechanistic events that facilitate the browning of white adipose tissue (WAT) in response to burns. Background: In hypermetabolic patients (eg, burns, cancer), the… read more here.
Keywords: macrophage; adipose tissue; white adipose; burn ... See more keywords
Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000688
Abstract: Obesity leads to multiple health problems, including diabetes, fatty liver, and even cancer. Here, we report that urolithin A (UA), a gut-microflora–derived metabolite of pomegranate ellagitannins (ETs), prevents diet-induced obesity and metabolic dysfunctions in mice… read more here.
Keywords: urolithin exerts; adipose tissue; browning white; thermogenesis ... See more keywords
DEPP Deficiency Contributes to Browning of White Adipose Tissue
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23126563
Abstract: Decidual protein induced by progesterone (DEPP) was originally identified as a modulator in the process of decidualization in the endometrium. Here, we define that DEPP is involved in adipose tissue thermogenesis, which contributes to metabolic… read more here.
Keywords: depp deficiency; adipose tissue; browning white; depp ... See more keywords
Cucurbitacin B-, E-, and I-Induced Browning of White Adipocytes Is Promoted by the Inhibition of Phospholipase D2
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315362
Abstract: The mechanism of white adipose tissue browning is not well understood; however, naturally occurring compounds are known to play a positive role. The effects of cucurbitacins B, E, and I on the browning of mature… read more here.
Keywords: inhibition; white adipocytes; mature; mature adipocytes ... See more keywords