Preoptic bombesin-like receptor-3 neurons heat it up
Sign Up to like & getrecommendations! Published in 2022 at "Temperature"
DOI: 10.1080/23328940.2022.2047574
Abstract: A defining characteristic of endotherms, including mammals, is a warm, highly regulated, and stable core body temperature (Tb). Identifying the network of neurons controlling Tb is essential for understanding this fundamental physiology. The preoptic area… read more here.
Keywords: neuronal populations; like receptor; brs3; bombesin like ... See more keywords
Constitutively active BRS3 is a genuinely orphan GPCR in placental mammals
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000175
Abstract: G protein–coupled receptors (GPCRs) play an important role in physiology and disease and represent the most productive drug targets. Orphan GPCRs, with their endogenous ligands unknown, were considered a source of drug targets and consequently… read more here.
Keywords: genuinely orphan; constitutively active; vertebrate brs3; gpcr ... See more keywords