Quassilactones A and B, structural characterization of a new class of norquassinoids from Brucea javanica
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-020-01407-8
Abstract: Two novel norquassinoids possessing a unique ketal skeleton, designated quassilactones A (1) and B (2), were isolated from the fruits of Brucea javanica (Simaroubaceae). Their structures were established by extensive NMR and HR-ESI-MS spectroscopic analysis.… read more here.
Keywords: new class; class norquassinoids; quassilactones structural; brucea javanica ... See more keywords
Quassinoids in Brucea javanica are potent stimulators of lipolysis in adipocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Fitoterapia"
DOI: 10.1016/j.fitote.2019.104250
Abstract: Obesity is associated with a number of metabolic disorders. Lipolysis is the initial step in the metabolism of lipids stored in adipocytes and is therefore considered a therapeutic target for obesity. Quassinoids are unique terpenes… read more here.
Keywords: brucea javanica; stimulators lipolysis; quassinoids brucea; potent stimulators ... See more keywords
Anti-inflammatory effects of Brucea javanica oil emulsion by suppressing NF-κB activation on dextran sulfate sodium-induced ulcerative colitis in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.01.042
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Brucea javanica is an important traditional medicinal herb used for the treatment of dysentery, malaria, inflammation and cancer in southeast Asia for many years. However, the anti-inflammatory mechanism of Brucea javanica in the… read more here.
Keywords: anti inflammatory; brucea javanica; dextran sulfate; treatment ... See more keywords
Brujavanoids A-U, structurally diverse apotirucallane-type triterpenoids from Brucea javanica and their anti-inflammatory effects.
Sign Up to like & getrecommendations! Published in 2022 at "Bioorganic chemistry"
DOI: 10.2139/ssrn.4135624
Abstract: Extensive phytochemical investigation on the methanol extract of the inflorescences, twigs, and leaves of Brucea javanica led to the isolation and identification of 27 triterpenoids, including 21 previously undescribed ones, named brujavanoids A-U (1-21). Their… read more here.
Keywords: anti inflammatory; type triterpenoids; brucea javanica; apotirucallane type ... See more keywords
Effect of FOLFOX4 combined with Brucea javanica emulsion on VEGF in patients with gastric cancer
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DOI: 10.3892/ol.2017.7429
Abstract: The aim of the study was to investigate the effect of FOLFOX4 regimen combined with Brucea javanica emulsion on the content of serum vascular endothelial growth factor (VEGF) in patients with gastric cancer, and to… read more here.
Keywords: gastric cancer; brucea javanica; group; combined brucea ... See more keywords