Detection of Brucella abortus by immunofluorescence assay using anti-16-kDa outer membrane protein (OMP16) antibody
Sign Up to like & getrecommendations! Published in 2017 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-017-2529-9
Abstract: Brucellosis in humans is one of the most important zoonotic diseases worldwide. This disease causes weakness, fever, pain, sweats, and complications in the liver, spleen, and lymphatic system; Brucellosis requires long-term antibiotic therapy. This study… read more here.
Keywords: protein; antibody; outer membrane; abortus ... See more keywords
Antigen-Specific Activation of Blood Lymphocytes in Mice Immunized with Brucella abortus 19 BA.
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of experimental biology and medicine"
DOI: 10.1007/s10517-020-04914-6
Abstract: We studied the expression of activation markers CD25 and CD69 by blood lymphocytes in white mice vaccinated with Brucella abortus 19 BA in antigen-specific tests in vitro. During incubation of blood lymphocytes with brucellosis polysaccharide-protein… read more here.
Keywords: antigen specific; blood lymphocytes; antigen; activation ... See more keywords
Synthesis, Characterization and Lipophilicity Study of Brucella abortus’ Immunogenic Peptide Sequence That Can Be Used in the Future Vaccination Studies
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-018-9739-0
Abstract: Brucellosis is primarily a zoonotic disease caused by members of the Brucella genus which consists of 11 recognized species based on pathogenicity and host preferences. Peptide vaccines are an alternative strategy to conventional vaccines based… read more here.
Keywords: peptide; peptide sequence; lipophilicity study; sequence ... See more keywords
Molecular characterization and antimicrobial susceptibility testing of clinical and non-clinical Brucella melitensis and Brucella abortus isolates from Egypt
Sign Up to like & getrecommendations! Published in 2021 at "One Health"
DOI: 10.1016/j.onehlt.2021.100255
Abstract: Brucellosis is a highly contagious and incapacitating disease of humans, livestock and wildlife species globally. Treatment of brucellosis in animals is not recommended, and in humans, combinations of antibiotics recommended by the World Health Organization… read more here.
Keywords: susceptibility testing; molecular characterization; brucella; brucella abortus ... See more keywords
Immunization of guinea pigs with Salmonella delivered anti-Brucella formulation reduces organs bacterial load and mitigates histopathological consequences of Brucella abortus 544 challenge.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2017.11.006
Abstract: With an objective to generate safe and effective anti-Brucella vaccine, an attenuated live Salmonella Typhimurium vector delivering heterologous Brucella immunogenic proteins SOD, Omp19, BLS, and PrpA formulated with purified Brucella abortus lipopolysaccharide was evaluated on… read more here.
Keywords: guinea; brucella; challenge; anti brucella ... See more keywords
Association of bovine major histocompatibility complex class I (BoLA-A) alleles with immune response to Brucella abortus strain 19 in calves.
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2019.108569
Abstract: In the present study, we analyzed the immune response of calves to Brucella abortus strain 19 vaccine (S19) and its association with MHC class I (BoLA-A) alleles (exons 2-3 and 4-5). Polymerase chain reaction-restriction fragment… read more here.
Keywords: bola alleles; response; class; immune response ... See more keywords
Immunization with a combination of recombinant Brucella abortus proteins induces T helper immune response and confers protection against wild‐type challenge in BALB/c mice
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14015
Abstract: Protective efficiency of a combination of four recombinant Brucella abortus (B. abortus) proteins, namely, ribosomal protein L7/L12, outer membrane protein (OMP) 22, OMP25 and OMP31, was evaluated as a combined subunit vaccine (CSV) against B.… read more here.
Keywords: abortus; recombinant brucella; csv; brucella ... See more keywords
Galectin‐3 regulates proinflammatory cytokine function and favours Brucella abortus chronic replication in macrophages and mice
Sign Up to like & getrecommendations! Published in 2021 at "Cellular Microbiology"
DOI: 10.1111/cmi.13375
Abstract: In this study, we provide evidence that galectin‐3 (Gal‐3) plays an important role in Brucella abortus infection. Our results showed increased Gal‐3 expression and secretion in B. abortus infected macrophages and mice. Additionally, our findings… read more here.
Keywords: brucella; galectin; macrophages mice; replication ... See more keywords
Brucella abortus–infected platelets modulate the activation of neutrophils
Sign Up to like & getrecommendations! Published in 2020 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12373
Abstract: Brucellosis is a contagious disease caused by bacteria of the genus Brucella. Platelets (PLTs) have been widely involved in the modulation of the immune response. We have previously reported the modulation of Brucella abortus–mediated infection… read more here.
Keywords: infected platelets; abortus infected; infection; brucella abortus ... See more keywords
Periplasmic protein EipA determines envelope stress resistance and virulence in Brucella abortus
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Microbiology"
DOI: 10.1111/mmi.14178
Abstract: Molecular components of the Brucella abortus cell envelope play a major role in its ability to infect, colonize and survive inside mammalian host cells. In this study, we have defined a role for a conserved… read more here.
Keywords: envelope stress; brucella; eipa; stress resistance ... See more keywords
Histidine auxotroph mutant is defective for cell separation and allows the identification of crucial factors for cell division in Brucella abortus
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Microbiology"
DOI: 10.1111/mmi.14956
Abstract: The pathogenic bacterium Brucella abortus invades and multiplies inside host cells. To grow inside host cells, B. abortus requires a functional histidine biosynthesis pathway. Here, we show that a B. abortus histidine auxotroph mutant also… read more here.
Keywords: abortus; cell division; brucella abortus; histidine auxotroph ... See more keywords