Novel diagnostic approach on the identification of Brucella melitensis Greek endemic strains‐discrimination from the vaccine strain Rev.1 by PCR‐RFLP assay
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.99
Abstract: Abstract Despite the intensive implementation of control programmes goat, sheep and human brucellosis remains endemic in Greece. As the discrimination between field endemic strains and vaccine strain Rev.1 is not feasible, it is essential to… read more here.
Keywords: vaccine strain; brucella melitensis; endemic strains; strain rev ... See more keywords
Duplex PCR for the diagnosis of Brucella melitensis and its differentiation from the REV-1 vaccine strain
Sign Up to like & getrecommendations! Published in 2017 at "Small Ruminant Research"
DOI: 10.1016/j.smallrumres.2016.11.004
Abstract: Abstract Caprine brucellosis is a chronic infectious disease caused by Brucella melitensis, whose main symptoms are abortion in females and orchitis in males. Vaccination by mistake of pregnant goats with the REV-1 vaccine may cause… read more here.
Keywords: rev vaccine; duplex pcr; brucella melitensis;
Brucella melitensis and B. abortus in eggs, larvae and engorged females of Dermacentor marginatus.
Sign Up to like & getrecommendations! Published in 2018 at "Ticks and tick-borne diseases"
DOI: 10.1016/j.ttbdis.2018.03.021
Abstract: Brucellosis is a relatively common zoonosis, particularly in the developing countries. Our aim was to cultivate the Brucella wild-type strain from eggs of Dermacentor marginatus, and to molecularly investigate the presence of Brucella DNA in… read more here.
Keywords: dermacentor marginatus; brucella; brucella melitensis; brucella dna ... See more keywords
Vaccine Candidate Brucella melitensis 16MΔvjbR Is Safe in a Pregnant Sheep Model and Confers Protection
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DOI: 10.1128/msphere.00120-20
Abstract: Brucellosis is one of the most commonly reported zoonotic disease with a worldwide distribution. Of the 12 Brucella species, Brucella melitensis is considered the most virulent and causes reproductive failure (abortions/stillbirths) in small ruminants, which… read more here.
Keywords: rev; 16m vjbr; brucella melitensis; melitensis ... See more keywords
A Brucella melitensis H38ΔwbkF rough mutant protects against Brucella ovis in rams
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Research"
DOI: 10.1186/s13567-022-01034-z
Abstract: Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economic losses and, although B. ovis is non-zoonotic, B. melitensis is the main cause of human brucellosis. B. melitensis carries a smooth… read more here.
Keywords: rough; h38 wbkf; melitensis; brucella melitensis ... See more keywords
Silver nanoparticle-conjugated antibiotics inhibit in vitro growth of Brucella melitensis
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary World"
DOI: 10.14202/vetworld.2022.1749-1752
Abstract: Background and Aim: Brucellosis is a contagious livestock disease with a significant economic impact. This study aimed to compare the efficacy of antibiotics used alone or in combination with silver nanoparticles (AgNPs) against Brucella melitensis… read more here.
Keywords: melitensis; brucella melitensis; silver; conjugated antibiotics ... See more keywords
Evaluation of the designed multi-epitope protein of Brucella melitensis in guinea pigs
Sign Up to like & getrecommendations! Published in 2021 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2021.54667.12267
Abstract: Objective(s): One of the causes of human and animal zoonotic infections is Brucella melitensis, which is transmitted to humans through dairy products. It seems for prevention of human infection we might protect the livestock by… read more here.
Keywords: protein; guinea; brucella melitensis; evaluation designed ... See more keywords
Efficient Immunization of BALB/c Mice against Pathogenic Brucella melitensis and B. ovis: Comparing Cell-Mediated and Protective Immune Responses Elicited by pCDNA3.1 and pVAX1 DNA Vaccines Coding for Omp31 of Brucella melitensis
Sign Up to like & getrecommendations! Published in 2021 at "Iranian Journal of Biotechnology"
DOI: 10.30498/ijb.2021.2618
Abstract: Background: Brucella spp. are intracellular pathogens, therefore cell-mediated immunity is the main response to inhibit survival and growth of the bacteria in vertebrate host. Objective: Many eukaryotic plasmid vectors are being used in setting up… read more here.
Keywords: dna vaccines; omp31; brucella melitensis; brucella ... See more keywords
Using a Relative Quantitative Proteomic Method to Identify Differentially Abundant Proteins in Brucella melitensis Biovar 3 and Brucella melitensis M5-90
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.929040
Abstract: Brucellosis, caused by Brucella spp., is one of the most widespread bacterial zoonoses worldwide. Vaccination is still considered the best way to control brucellosis. An investigation into the differential proteome expression patterns of wild and… read more here.
Keywords: melitensis; virulence; melitensis biovar; brucella melitensis ... See more keywords
Proteome-Wide Screening of Potential Vaccine Targets against Brucella melitensis
Sign Up to like & getrecommendations! Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11020263
Abstract: The ongoing antibiotic-resistance crisis is becoming a global problem affecting public health. Urgent efforts are required to design novel therapeutics against pathogenic bacterial species. Brucella melitensis is an etiological agent of brucellosis, which mostly affects… read more here.
Keywords: kcal mol; water; vaccine; brucella melitensis ... See more keywords
Geographical distribution of Brucella melitensis inferred from rpoB gene variation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of infection in developing countries"
DOI: 10.3855/jidc.7598
Abstract: INTRODUCTION Currently available tests have limitations for the identification of Brucella species and strains, and their genetic lineage. The genome sequence of the rpoB gene encoding the β-subunit of DNA-dependent RNA polymerase was investigated for… read more here.
Keywords: rpob gene; gene; geographical distribution; brucella melitensis ... See more keywords