Natural Products Sulforaphane and Brusatol Modulate NRF2 in Bovine Mammary Cells
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DOI: 10.1093/cdn/nzaa045_030
Abstract: The objectives were to analyze the effect of the natural isothiocyanate sulforaphane, an agonist of NRF2, and the natural quassinoid brusatol, an NRF2 antagonist, on modulation of NRF2 in bovine mammary cells. The effects of… read more here.
Keywords: nrf2 bovine; mammary cells; activation; brusatol ... See more keywords
Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway
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DOI: 10.1155/2018/2360427
Abstract: Although gemcitabine is the standard chemotherapy treatment for advanced pancreatic cancer, its benefits are quite limited due to prevalent chemoresistance, and the mechanism underlying gemcitabine chemoresistance remains unclear. Currently, Nrf2 has been deemed as a… read more here.
Keywords: gemcitabine; brusatol; pancreatic cancer; cancer cells ... See more keywords
Larvicidal Activity of Brusatol Isolated from Brucea javanica (L) Merr on Culex quinquefasciatus
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DOI: 10.18502/ijph.v48i4.1002
Abstract: Background: Vector control is still emphasized on the using of chemical insecticide which can cause death of non-target organisms, pollution and vector resistance. Therefore, natural insecticides/larvicides are an alternative to using chemical insecticides to control… read more here.
Keywords: control; brusatol; brusatol isolated; javanica merr ... See more keywords