Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer-Assisted Compaction.
Sign Up to like & getrecommendations! Published in 2017 at "Small"
DOI: 10.1002/smll.201701432
Abstract: Unwanted stimulation of the innate immune system by foreign nucleic acids has been one of the major barriers preventing bioactive sequences from reaching market. Foreign nucleic acids can be recognized by multiple pattern recognition receptors… read more here.
Keywords: modulating cellular; immune system; immune response; brush polymer ... See more keywords
Comparison of the Anti-inflammatory Activity and Cellular Interaction of Brush Polymer-N-Acetyl Cysteine Conjugates in Human and Murine Microglial Cell Lines.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.3c00140
Abstract: Microglia-mediated neuroinflammation is commonly associated with neurodegeneration and has been implicated in several neurological disorders, such as Alzheimer's disease and Parkinson's disease. Therefore, it is crucial to develop a detailed understanding of the interaction of… read more here.
Keywords: brush polymer; anti inflammatory; cell; brush polymers ... See more keywords